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Billionaire Stan Druckenmiller’s 10 Small and Mid-Cap Stock Picks with Huge Upside Potential

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Stanley Druckenmiller, the chief of New York-based investment firm Duquesne Capital, oversees a 13F portfolio at his hedge fund that was worth close to $4.5 billion at the end of the fourth quarter of 2025. Druckenmiller, whose net worth is close to $8 billion, recently sat down for a conversation with Iliana Bouzali, Global Head of Derivatives Distribution and Structuring at Morgan Stanley. During this interview, he discussed his evolving investment philosophy, the role of instinct versus analysis, and his current market positioning. Druckenmiller emphasized that extreme success in markets often came from a “narrow form of intelligence” and the ability to pull the trigger on high-conviction ideas, even before all the data is in.

READ MORE: 15 Best Stocks to Buy According to Billionaire Ray Dalio.

Looking ahead, Druckenmiller said he was shifting away from the AI-heavy portfolio that drove his returns over the last three years. He said he expected a strong US economy driven by government stimulus and a Fed that was “probably going to cut.” Outlining his views on the dollar and commodities, he noted that he was “bearish on the US dollar… mainly because foreigners are way, way overloaded in dollars. He added that he was also long on copper, mainly because, “There’s no supply coming on… very tight for the next 8 years.” The Billionaire also outlined why he was shorting bonds, noting it was a hedge against growth-driven inflation. “I don’t necessarily expect to make money short bonds… but it allows me to hold the other assets I mentioned,” he said.

READ MORE: 10 Best Stocks to Buy According to Billionaire Paul Tudor Jones.

Stan Druckenmiller

Our Methodology

To compile our list of Billionaire Stan Druckenmiller’s small and mid-cap stock picks with huge upside potential, we reviewed the latest 13F filings of Duquesne Capital. Next, we focused on the top stocks in his portfolio that are in the mid and small cap range. Data for the hedge fund sentiment surrounding each stock was taken from Insider Monkey’s Q4 2025 database of 1041 elite hedge funds.

Why are we interested in the stocks that hedge funds pile into? The reason is simple: our research has shown that we can outperform the market by imitating the top stock picks of the best hedge funds. Our quarterly newsletter’s strategy selects 14 small-cap and large-cap stocks every quarter and has returned 498.7% since May 2014, beating its benchmark by 303 percentage points (see more details here).

Billionaire Stan Druckenmiller’s Small and Mid-Cap Stock Picks with Huge Upside Potential

10. Entegris, Inc. (NASDAQ:ENTG)

Duquesne Capital’s Stake: $71 Million 

Duquesne Capital has disclosed a stake in Entegris, Inc. (NASDAQ:ENTG) stock in three filings over the past four years. The first of these was disclosed in the fourth quarter of 2022. It comprised 55,000 shares and was sold off within months. The second was revealed in filings for the second quarter of 2025. This comprised 1.6 million shares and was sold before the end of the third quarter of 2025. A new position was opened in filings for the fourth quarter of 2025. This holding comprises just under 850,000 shares.

Hedge funds are piling into Entegris, Inc. (NASDAQ:ENTG) because it is one of the few companies providing the materials integrity necessary for the next generation of chips. As chipmakers transition to 2nm and 3nm nodes for AI processors, the tolerance for contamination drops to zero. Entegris dominates the market for liquid filtration and high-purity chemicals required for these processes. Institutional investors also often reward companies that fix their balance sheets. Hedge funds have noted Entegris’s aggressive debt reduction plan. In 2025, the company generated $404 million in free cash flow. Management has committed to reducing its net leverage to below 3.5x by the end of 2026.

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The $250 Trillion AI Hype is Real. A few years from now, you’ll probably wish you’d bought this stock.

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Fast forward a year and Amazon’s new CEO Andy Jassy described generative AI as a “once-in-a-lifetime” technology that is already being used across Amazon to reinvent customer experiences.

At the 8th Future Investment Initiative conference, Elon Musk predicted that by 2040 there would be at least 10 billion humanoid robots, with each priced between $20,000 and $25,000.

Do the math. According to Musk, this technology could be worth $250 trillion by 2040.

Put another way, that’s roughly equal to:

  • 175 Teslas
  • 107 Amazons
  • 140 Metas
  • 84 Googles
  • 65 Microsofts
  • And 55 Nvidias

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  • Bill Gates sees artificial intelligence as the “biggest technological advance in my lifetime,” more transformative than the internet or personal computer, capable of improving healthcare, education, and addressing climate change.
  • Larry Ellison — through Oracle, is spending billions on Nvidia chips and partnering with Cohere to embed generative AI across Oracle’s cloud and apps.
  • Warren Buffett — not known for tech hype — says this breakthrough could have a ‘hugely beneficial social impact.

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