Billionaire Philippe Laffont’s 10 Stock Picks with Huge Upside Potential

6. Intuitive Surgical, Inc. (NASDAQ:ISRG)

Number of Hedge Fund Holders: 107

Upside Potential: 30.48%

Share Price Return Between July 1 and October 15: -19.03%

Coatue Management holds $400.81 million worth of shares in Intuitive Surgical, Inc. (NASDAQ:ISRG), representing 1.12% of its total 13F portfolio, helping the stock secure a place on our list of billionaire Philippe Laffont’s 10 stock picks with huge upside potential.

New AI-driven software advancements received approval from the U.S. FDA for the company’s Ion Endoluminal System, Intuitive Surgical, Inc. (NASDAQ:ISRG) announced on October 8. The Ion Endoluminal System is a robotic-assisted bronchoscopy platform used for lung biopsies.

With this upgrade, the Ion Endoluminal System integrates artificial intelligence and advanced imaging across the system’s navigational workflow. This integration is expected to enhance accuracy and efficiency in diagnosing lung nodules, which are key to early lung cancer detection. Furthermore, the upgrade features real-time updates through integrated tomosynthesis. These updates are expected to expand access to advanced imaging in varied clinical settings.

Intuitive Surgical, Inc. (NASDAQ:ISRG) strengthens its leadership in minimally invasive care through this upgrade, with the limited U.S. rollout in 2025 preceding a broader 2026 launch, reinforcing its innovation-driven growth trajectory.

Intuitive Surgical, Inc. (NASDAQ:ISRG), a global technology leader in robotic-assisted minimally invasive surgery, is known for its da Vinci and Ion systems. The company enables precision procedures and enhanced patient outcomes. It is included in Philippe Laffont’s stock portfolio.