Conestoga Capital Advisors, an asset management company, released its fourth-quarter 2025 investor letter. US equities experienced solid returns in 2025, with double-digit gains across all major indices. A copy of the letter can be downloaded here. In 2025, the Conestoga Micro Cap Composite met its purpose of preserving capital during negative market returns and capturing upside during strong market returns. Micro Caps faced significant volatility in 2025. During the course of events, Conestoga Micro Cap Composite returned -1.91% net of fees in the fourth quarter and 16.24% net of fees for the full year 2025, trailing the Russell Microcap Growth Index’s 2.14% and 21.84% gains in the fourth quarter and full year, respectively. Please review the Strategy’s top five holdings to gain insights into their key selections for 2025.
In its fourth-quarter 2025 investor letter, Conestoga Capital Advisors highlighted stocks like Alpha Teknova, Inc. (NASDAQ:TKNO). Alpha Teknova, Inc. (NASDAQ:TKNO) is a biotechnology company that provides critical reagents for the discovery, development, and commercialization of novel therapies. On February 19, 2026, Alpha Teknova, Inc. (NASDAQ:TKNO) stock closed at $2.09 per share. One-month return of Alpha Teknova, Inc. (NASDAQ:TKNO) was -37.05%, and its shares lost 71.95% over the past 52 weeks. Alpha Teknova, Inc. (NASDAQ:TKNO) has a market capitalization of $111.876 million.
Conestoga Capital Advisors stated the following regarding Alpha Teknova, Inc. (NASDAQ:TKNO) in its fourth quarter 2025 investor letter:
“Alpha Teknova, Inc. (NASDAQ:TKNO) is a leading provider of critical reagents that enable the discovery, development, and production of biopharmaceutical products such as drug therapies, novel vaccines, and molecular diagnostics. The company reported a solid quarter and pointed to positive leading indicators in end markets driven by biotech funding and nice growth with large pharma companies. That said, the positive leading indicators have not yet translated into sales, and investors continue with a “wait-and-see” approach to a recovery in early-stage biotech funding.”
Alpha Teknova, Inc. (NASDAQ:TKNO) is not on our list of 30 Most Popular Stocks Among Hedge Funds. According to our database, 12 hedge fund portfolios held Alpha Teknova, Inc. (NASDAQ:TKNO) at the end of the third quarter, up from 11 in the previous quarter. While we acknowledge the risk and potential of Alpha Teknova, Inc. (NASDAQ:TKNO) as an investment, our conviction lies in the belief that some AI stocks hold greater promise for delivering higher returns and doing so within a shorter time frame. If you are looking for an AI stock that is more promising than Alpha Teknova, Inc. (NASDAQ:TKNO) and that has 10,000% upside potential, check out our report about this cheapest AI stock.
In another article, we covered Alpha Teknova, Inc. (NASDAQ:TKNO) and shared Conestoga Capital Advisors’ views on the company in the previous quarter. In addition, please check out our hedge fund investor letters Q4 2025 page for more investor letters from hedge funds and other leading investors.
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Disclosure: None. This article is originally published at Insider Monkey.
