In this article, we will list the 5 Most Profitable NYSE Stocks to Invest In. Please visit 7 Most Profitable NYSE Stocks to Invest In if you would like to see the extended list and the methodology behind it.

5. ONEOK, Inc. (NYSE:OKE)
ONEOK, Inc. (NYSE:OKE) is one of the most profitable NYSE stocks to invest in. ONEOK, Inc. (NYSE:OKE) was upgraded to Overweight from Equal Weight by Wells Fargo on March 25, with the firm lifting the price target on the stock to $100 from $81. The firm believes that the Iran war will create a “structural shift” in global energy markets, including midstream, and will also boost demand for U.S. energy. It further told investors in a research note that it anticipates Permian gas and natural gas liquids supply to accelerate to meet this growing demand, and thus upgraded three names in midstream energy.
In another development, Truist initiated coverage of ONEOK, Inc. (NYSE:OKE) with a Hold rating on March 23, setting a price target of $91. The firm believes that the company stands out as a large-cap, and supported this claim by citing its assets across natural gas liquids, gas pipelines, crude and refined products, with a focus on the Bakken and Mid-Con, while also expanding into the Permian and Haynesville through M&A.
ONEOK, Inc. (NYSE:OKE) gathers, fractionates, processes, transports, stores, and markets natural gas. The company’s operations are divided into the following segments: Natural Gas Gathering and Processing, Natural Gas Liquids and Natural Gas Pipelines.
4. Range Resources Corporation (NYSE:RRC)
Range Resources Corporation (NYSE:RRC) is one of the most profitable NYSE stocks to invest in. Truist initiated coverage of Range Resources Corporation (NYSE:RRC) with a Hold rating on March 23, setting a price target of $48. The firm told investors that it likes the stock’s story that revolves around capital-efficient growth over the next several years, capitalizing on incremental processing capacity and freed-up egress. However, Truist also argued that these attributes are already embedded in the stock price.
Range Resources Corporation (NYSE:RRC) also received a rating update from JPMorgan on March 20, with the firm lifting the price target on the stock to $46 from $41 while maintaining an Underweight rating on the shares. The firm told investors in a research note that the oil market fundamentals “shifted on a dime” because of the conflict in the Middle East, adding that the war has resulted in a considerable reduction in the global productive capacity and “quickly evaporated the risk” of a supply glut in 2026 following the closure of the Strait of Hormuz. The firm also said that it would not be surprised to see a $5-$10 per barrel geopolitical risk premium embedded into the long-end of the oil price curve.
Range Resources Corporation (NYSE:RRC) is involved in the exploration, development, and acquisition of natural gas and oil properties in the Appalachian and Midcontinent regions.
3. Coeur Mining, Inc. (NYSE:CDE)
Coeur Mining, Inc. (NYSE:CDE) is one of the most profitable NYSE stocks to invest in. Coeur Mining, Inc. (NYSE:CDE) was upgraded to Outperform from Sector Perform by ATB Capital on March 24, with the firm setting a price target of C$25. The rating update came after the company provided a corporate update on March 23, following the completion of the acquisition of New Gold Inc. on March 20. It also reported that the new Afton and Rainy River contribute strong additions to Coeur Mining, Inc.’s (NYSE:CDE) updated 2026 consolidated production guidance, with the company expecting 2026 consolidated gold, silver, and copper production of 680,000 – 815,000 ounces, 18.7 – 21.9 million ounces, and 50 – 65 million pounds, respectively. Management stated that this incorporates nine months of contribution from its two new Canadian mines. For perspective, the company’s 2025 production totaled 419,046 gold ounces and 17.9 million silver ounces.
Coeur Mining, Inc. (NYSE:CDE) also stated that its Board of Directors authorized an expanded $750 million share repurchase program, along with an inaugural $0.02 per share semiannual dividend policy expected to be paid in June and December of each year.
Coeur Mining, Inc. (NYSE:CDE) explores and develops gold and silver mines and mining properties in the US, Canada, and Mexico. It operates through the Palmarejo, Rochester, Kensington, Wharf, and Other segments. The Palmarejo segment manages a gold-silver complex, while the Rochester segment operates a silver-gold mine in northwestern Nevada. Similarly, the Kensington and Wharf segments operate an underground gold mine and an open-pit heap leach gold mine, respectively.
2. EQT Corporation (NYSE:EQT)
EQT Corporation (NYSE:EQT) is one of the most profitable NYSE stocks to invest in. Truist initiated coverage of EQT Corporation (NYSE:EQT) with a Buy rating and $74 price target on March 23, telling investors in a research note that the company “stands out” as the largest Appalachian pure-play natural gas levered exploration and production company that holds core acreage in Pennsylvania, West Virginia, and Ohio targeting the Marcellus Shale. It further stated that EQT Corporation (NYSE:EQT) is best positioned to capture upside from the improving natural gas backdrop.
In another development, Bernstein cut the price target on EQT Corporation (NYSE:EQT) to $69 from $73 on March 22, reiterating an Outperform rating on the shares. The firm updated models in the energy and transportation group to take into account the current crude prices and crack spreads, “while acknowledging a wide range of future outcomes.” It further stated that the wars that do not end within weeks typically continue for years, and given the “uncertainty and right tail risk”, Bernstein continues to recommend adding energy exposure.
EQT Corporation (NYSE:EQT) is a natural gas production company involved in the provision of supply, transmission, and distribution of natural gas.
1. Vertiv Holdings Co (NYSE:VRT)
Vertiv Holdings Co (NYSE:VRT) is one of the most profitable NYSE stocks to invest in. Vertiv Holdings Co (NYSE:VRT) announced on March 26 four new or expanding manufacturing facilities in the Americas, expanding its production capacity for power management, infrastructure solutions, and integrated cabinets. The company announced two additional manufacturing facilities in South Carolina, an additional facility in Pennsylvania launched by its racks and containment business, and an expansion in Mexicali, Mexico.
In another development, HSBC initiated coverage of Vertiv Holdings Co (NYSE:VRT) with a Buy rating and $325 price target on March 25, telling investors in a research note that the company is a leading critical infrastructure provider for data centers as well as an “important enabler” of AI growth. Its solutions across the power and thermal management systems support its position. The firm also stated that it sees a “highly attractive” long-term growth outlook for data centers, and expects Vertiv Holdings Co (NYSE:VRT) to be a “significant beneficiary of these favorable tailwinds”. It predicts 36% annual earnings growth for the company through 2028.
Vertiv Holdings Co (NYSE:VRT) designs, manufactures, and services critical digital infrastructure technology for communication networks, data centers, and commercial and industrial environments. It also offers thermal management products, power management products, switchgear and busbar products, integrated rack systems, modular solutions, and more. The company’s operations are divided into the following geographical segments: Americas, Asia Pacific, and Europe, the Middle East, and Africa (EMEA).
While we acknowledge the potential of VRT to grow, our conviction lies in the belief that some AI stocks hold greater promise for delivering higher returns and have limited downside risk. If you are looking for an AI stock that is more promising than VRT and that has 100x upside potential, check out our report about the cheapest AI stock.
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