In this article, we will list the 5 Most Buzzing Stocks to Buy with the Highest Upside Potential. Please visit 11 Most Buzzing Stocks to Buy with the Highest Upside Potential to see the extended list and the methodology behind it.

5. ImmunityBio Inc. (NASDAQ:IBRX)

ImmunityBio Inc. (NASDAQ:IBRX) is one of the most buzzing stocks to buy with the highest upside potential. On March 9, ImmunityBio announced the resubmission of its sBLA to the FDA for ANKTIVA in combination with Bacillus Calmette-Guérin/BCG. This filing specifically targets patients with BCG-unresponsive non-muscle invasive bladder cancer/NMIBC who present with papillary disease. The resubmission follows an initial review in early 2026, during which the FDA requested additional long-term efficacy and follow-up data to support the treatment’s potential in this specific patient population.

The sBLA is supported by results from the QUILT 3.032 Phase 2/3 trial, which showed durable outcomes for patients with high-grade papillary-only disease. Data published in The Journal of Urology showed a 12-month disease-free survival rate of 58.2% and a bladder preservation rate of 81.8% at 36 months. These findings highlight ANKTIVA’s role as an IL-15 superagonist that activates natural killer and killer T cells to prevent progression to muscle-invasive disease without the need for chemotherapy.

Beyond this NMIBC indication, ImmunityBio is expanding its global regulatory reach, noting that the Saudi Food and Drug Authority recently approved ANKTIVA for certain metastatic non-small cell lung cancers. ImmunityBio Inc. (NASDAQ:IBRX) remains in discussions with the FDA and other international agencies regarding the use of its immunotherapy platform for various advanced cancers. Currently, the FDA has acknowledged receipt of the papillary NMIBC resubmission as it continues to evaluate the updated clinical data.

ImmunityBio Inc. (NASDAQ:IBRX) is a biotechnology company that innovates, develops, and commercializes next-generation immunotherapies designed to activate the patient’s immune system and deliver durable protection against cancer and infectious diseases.

4. Infosys Limited (NYSE:INFY)

Infosys Limited (NYSE:INFY) is one of the most buzzing stocks to buy with the highest upside potential. On March 10, Infosys and Incora entered into a multi-year strategic collaboration to integrate AI throughout Incora’s global supply chain operations. The partnership will deploy AI-enabled capabilities across more than 60 countries to modernize Incora’s existing multi-ERP landscape. By combining Infosys’ digital consulting expertise with Incora’s specialized knowledge in aerospace and defense, the initiative seeks to create a more resilient and responsive global enterprise.

The collaboration centers on the implementation of Infosys Topaz and the EdgeVerve AI Next Platform to harmonize data and processes. This AI-first approach is designed to be non-intrusive, allowing for the orchestration of complex, multi-system environments without disrupting daily operations. The goal is to provide greater visibility and accuracy across core workflows, reducing operational friction and enabling faster, data-driven decision-making for Incora’s customers.

This alliance reflects a broader shift in the aerospace and defense industry toward scalable, AI-enabled operating models that address the challenges of fragmented data and legacy systems. Executives from both companies highlighted that the pairing of advanced AI platforms with a global supply chain footprint will set new benchmarks for efficiency and operational excellence.

Infosys Limited (NYSE:INFY), together with its subsidiaries, provides consulting, technology, outsourcing, and digital services in North America, Europe, India, Switzerland, and internationally.

3. First Majestic Silver Corp. (NYSE:AG)

First Majestic Silver Corp. (NYSE:AG) is one of the most buzzing stocks to buy with the highest upside potential. On March 11, First Majestic Silver announced results from its 2025 exploration program at the Jerritt Canyon Gold Mine in Nevada. The campaign included ~18,300 meters of drilling across 57 holes, focusing on targets such as Mahala, Javelin, and Saval. According to the CEO, the findings reinforce the potential for expanding Mineral Resources in the district, identifying opportunities for both near-surface open-pit and deeper underground mining across the company’s 30,000-hectare land package.

Significant drilling highlights were reported in the Mahala-to-Javelin expansion corridor, located between the Smith and SSX mines. Surface drilling at the Javelin target indicated that the gold mineralized zone is thicker than previously modeled, with notable intercepts including 7.6 meters at 9.43 g/t Au. At the Mahala target, exploration east of the known resource boundary intersected 24.4 meters grading 3.44 g/t Au, suggesting that mineralization remains open toward Javelin and potentially above the water table in rising stratigraphy.

The 2025 program also evaluated shallow mineralization near historical open pits at the Saval target. In the East Saval area, drill hole SC-25-003 yielded an interval of 51.8 meters grading 1.48 g/t Au, which may represent an extension of the Saval trend or a link to the underground SSX Gridiron target. These results, alongside various intercepts at the Boilermaker, Murray, and Winter’s Creek areas, provide a foundation for further investment to define the geometry and continuity of these gold-bearing systems.

First Majestic Silver Corp. (NYSE:AG) acquires, explores, develops, and produces mineral properties in North America. The company explores for silver and gold deposits.

2. Advanced Micro Devices Inc. (NASDAQ:AMD)

Advanced Micro Devices Inc. (NASDAQ:AMD) is one of the most buzzing stocks to buy with the highest upside potential. On March 16, AMD and Celestica (NYSE:CLS) announced a collaboration to bring ‘Helios’, an open standards-based rack-scale AI platform, to the market. This partnership combines AMD’s leadership in HPC with Celestica’s expertise in advanced networking switch technologies and global manufacturing. The initiative aims to provide a new blueprint for AI infrastructure, specifically designed to handle the most demanding workloads of the next era across cloud, enterprise, and research environments.

Under the agreement, Celestica will manage the R&D, design, and manufacturing of scale-up networking switches within the Helios architecture. These switches are based on the Open Compute Project/OCP and Open-Rack-Wide/ORW form factors, using advanced silicon to enable high-speed interconnects. This infrastructure is specifically optimized for next-gen AMD Instinct MI450 Series GPUs, allowing for the creation of large-scale AI clusters with leading-edge computing power.

The Helios platform utilizes the Ultra Accelerator Link over Ethernet/UALoE architecture to ensure efficient scale-up connectivity while maintaining an open standards-based design. By using Celestica’s supply chain and engineering capabilities alongside AMD’s AI-optimized hardware, the collaboration seeks to reduce time-to-value and improve resiliency for organizations investing in AI infrastructure. The AMD Helios platform is expected to be available to customers in late 2026.

Advanced Micro Devices Inc. (NASDAQ:AMD) operates as a semiconductor company internationally. It operates in three segments: Data Center, Client and Gaming, and Embedded.

1. Broadcom Inc. (NASDAQ:AVGO)

Broadcom Inc. (NASDAQ:AVGO) is one of the most buzzing stocks to buy with the highest upside potential. On March 12, Broadcom announced the production volume shipping of its Tomahawk 6 family switch series, marking the arrival of the world’s first 102.4 Tbps switch. This release follows a rapid transition from initial sampling to full deployment in less than three quarters. Designed to meet the networking demands of massive AI clusters, the series doubles the throughput of the previous generation and supports both 100G and 200G SerDes to provide unmatched performance for scale-out and scale-up AI environments.

The Tomahawk 6 is highly optimized for AI training and inference, featuring advanced load balancing and congestion management to improve network utilization and reduce job completion times. For scale-out networks, the platform enables a 128K-XPU network using only two switch tiers, which simplifies connectivity and reduces latency. In scale-up architectures, a single chip can connect 512 XPUs with single-hop all-to-all connectivity, offering the industry’s most comprehensive set of routing features for clusters exceeding one million XPUs.

Beyond raw speed, the Tomahawk 6 family focuses on system-level power efficiency and cost reduction through Broadcom Inc.’s (NASDAQ:AVGO) SerDes and optics ecosystem. The technology provides the longest reach for passive copper interconnects, ensuring high reliability and a lower total cost of ownership. By offering 512 200G or 1024 100G SerDes on a single chip, the platform allows operators to deploy high-density AI clusters with fewer switch tiers and reduced optical complexity.

Broadcom Inc. (NASDAQ:AVGO) is a global technology firm that designs, develops, and supplies various semiconductor devices and infrastructure software solutions internationally.

While we acknowledge the potential of AVGO to grow, our conviction lies in the belief that some AI stocks hold greater promise for delivering higher returns and have limited downside risk. If you are looking for an AI stock that is more promising than AVGO and that has 100x upside potential, check out our report about the cheapest AI stock.

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