5 Largest Orthopedic Companies in the World

2. DePuy Synthes Companies

2021 Orthopedic Revenue: $8.5 billion

DePuy Synthes Companies is an orthopedic and neurosurgery company that is a part of New Brunswick, New Jersey-based consumer goods, pharmaceutical, and medical devices giant Johnson & Johnson Inc (NYSE:JNJ).

The company has recently launched the INHANCE Shoulder System as an innovation in shoulder replacement technology. The portfolio of DePuy Synthes is considered one of the most diverse in the field of orthopedics as it covers a broad range of segments ranging from joint reconstruction, spinal surgery, trauma, and sports medicine. In October 2022, DePuy Synthes Companies received 510(k) approval from the US FDA for its TELIGEN system, which provides digitalization tools for visualization.