5 Largest Biotech Companies in the US

4. Merck & Co., Inc. (NYSE:MRK)

2022 Revenue: $59.3 billion

Merck & Co. is an American biotech and pharmaceutical company that develops and produces vaccines, medicines, and therapies for human and animal health. In Q1 of 2023, the company experienced a decrease of $1.4 billion in sales, compared to the first quarter of 2022. However, the sales revenue still exceeded the expectations of analysts for the given time period.