5 Deadliest Cancers in the U.S.

2. Colorectal Cancer

Estimated Deaths: 52,550 

Colorectal cancer, commonly known as colon cancer, is a type of cancer that begins in the large intestine (colon). While colon cancer primarily impacts older adults, it can occur at any stage of life. The disease typically initiates with the development of small, noncancerous clusters of cells called polyps along the inner lining of the colon. Over time, certain polyps have the potential to transform into colon cancers. Excluding skin cancers, colorectal cancer is the third most common cancer diagnosed in both men and women in the United States.