5 Best US Stocks to Buy and Hold for the Next 5 Years

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1. NVIDIA Corporation (NASDAQ:NVDA)

Number of Hedge Fund Holders: 275

NVIDIA Corporation (NASDAQ:NVDA) is one of the best US stocks to buy and hold for the next 5 years. On June 16, HPE expanded its “HPE AI Factory with NVIDIA (NVDA)” portfolio to better support agentic AI, adding the NVIDIA Vera CPU for agent orchestration and the NVIDIA Agent Toolkit to safely manage autonomous multi-agent systems. These tools enable enterprises to move agentic workflows from development into secure, governed production environments.

To strengthen security, HPE is integrating NVIDIA Confidential Computing across its entire AI Factory line, providing hardware-based protection for sensitive data and models during execution. This ensures that proprietary information is safeguarded through cryptographic attestation, even as it is processed within complex AI pipelines.

The portfolio also gains enhanced full-stack integration featuring new NVIDIA Blackwell GPUs and high-performance networking like Spectrum-X Ethernet and BlueField DPUs. These updates provide the robust infrastructure necessary to scale next-generation AI factories while maintaining the performance required for high-speed data communication.

NVIDIA Corporation (NASDAQ:NVDA) is a fabless semiconductor and AI computing company that designs GPUs, AI accelerators, Application Programming Interfaces (APIs), and system-on-a-chip units. Through its CUDA ecosystem, the company enables industries ranging from autonomous vehicles to scientific research by advancing AI, accelerated computing, and data center infrastructure.

While we acknowledge the potential of NVDA to grow, our conviction lies in the belief that some AI stocks hold greater promise for delivering higher returns and have limited downside risk. If you are looking for an AI stock that is more promising than NVDA and that has 100x upside potential, check out our report about the cheapest AI stock.

READ NEXT: 10 Best Up and Coming Stocks to Buy for the Next 3 Years and 10 Most Undervalued Stocks to Buy and Hold for 2 Years.

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