5 Best Penny Stocks That Could Skyrocket in 2026

​2. Precigen, Inc. (NASDAQ:PGEN)

Number of Hedge Fund Holders: 29

Upside Potential: 180.90%

Precigen, Inc. (NASDAQ:PGEN) is one of the Best Penny Stocks That Could Skyrocket in 2026. On June 2, H.C. Wainwright reiterated a Buy rating on Precigen, Inc. (NASDAQ:PGEN) with a price target of $14. The reiterated bullish sentiment comes after the company presented data for PAPZIMEOS at a major oncology conference on May 30.

​PAPZIMEOS is the company’s treatment for recurrent respiratory papillomatosis, which is a condition where tumors grow in the airways. The long-term follow-up data from the pivotal study of PAPZIMEOS were presented at the American Society of Clinical Oncology’s annual meeting. Results showed that 15 out of 18 responders, around 83%, demonstrated ongoing complete response for at least 36 months, without requiring any additional treatment for RRP. Notably, 5 complete responders have ongoing responses beyond 4 years.

​The firm noted that durability was a key highlight of the presentation, as every complete responder had at least three years of follow-up, with some tracked for up to 51 months. Notably, the median duration of complete response has not yet been reached. H.C. Wainwright sees this data as further validation of PAPZIMEOS and maintains its positive outlook on the stock.

Precigen, Inc. (NASDAQ:PGEN) is a clinical-stage biopharmaceutical company developing gene and cell therapies.