5 Best Low Priced Stocks to Get Rich in 2026

Page 5 of 5

1. Upstream Bio, Inc. (NASDAQ:UPB)

Upside Potential as of June 18, 2026: 572.00%

Number of Hedge Fund Holders: 34

On June 12, JPMorgan significantly trimmed the price target on Upstream Bio, Inc. (NASDAQ:UPB) to $8 from $35, while downgrading the stock from Overweight to Neutral. In a research note, the analyst said that other peers in asthma are also set to generate new data over the course of the company’s Verekitug’s late-stage development. Thus, the results from these competitors are important to understand where the company’s product stands.

According to JPMorgan, the rest of the year and beyond appear as an execution period for the company, with “relatively sparse near-term stock-moving catalysts.” The firm finds it difficult to see a path to upside in the near term, especially given the company’s additional cash needs to power phase 3 development. The company’s negative returns are understandable, considering its 572% upside potential. With strong potential for future gains, Upstream Bio, Inc. (NASDAQ:UPB) is among the best low-priced stocks to get rich in 2026.

Back on June 3, Matthew Caufield from H.C. Wainwright began coverage of Upstream Bio, Inc. (NASDAQ:UPB) with a Buy rating and $36 price target. The analyst believes Verekitug is a novel antibody antagonist of the thymic stromal lymphopoietin receptor, with “sights on efficacy and differentiated quarterly subcutaneous dosing.”

Upstream Bio, Inc. (NASDAQ:UPB), incorporated in 2021, is a Massachusetts-based clinical-stage biotechnology company specializing in solutions for severe respiratory disorders.

While we acknowledge the potential of UPB to grow, our conviction lies in the belief that some AI stocks hold greater promise for delivering higher returns and have limited downside risk. If you are looking for an AI stock that is more promising than UPB and that has 100x upside potential, check out our report about the cheapest AI stock.

READ NEXT: Starter Stock Portfolio: 14 Safe Stocks to Buy Now and 40 Most Popular Stocks Among Hedge Funds Heading Into 2026.

Disclosure: None. Insider Monkey focuses on uncovering the best investment ideas of hedge funds and insiders. Please subscribe to our free daily e-newsletter to get the latest investment ideas from hedge funds’ investor letters by entering your email address below.

Page 5 of 5
1281292 - 11759070 - 1