In this article, we are going to look at the 5 Best Large Cap Stocks to Invest In Right Now. For a longer list and more details on how we picked these stocks, you can go to 8 Best Large Cap Stocks to Invest In Right Now.
5. The Walt Disney Company (NYSE:DIS)
The Walt Disney Company (NYSE:DIS) is one of the best large-cap stocks to invest in right now. On April 14, Reuters reported that The Walt Disney Company (NYSE:DIS) has decided to lay off employees as part of a plan to streamline its operations. The decision was announced by the company’s new chief executive, Josh D’Amaro, in an email to employees.
Around 1,000 jobs will be cut, according to a person familiar with the matter. The layoffs will mainly affect the marketing group, which was reorganized in January, along with other areas like the company’s studio and television business, ESPN, products and technology, and certain corporate functions.

According to the report by Reuters, The Walt Disney Company (NYSE:DIS), like other Hollywood studios, is facing changing economic conditions. This includes a decline in the television business, a shrinking box office, and growing competition in the industry.
In his email to employees, D’Amaro said the company needs to adapt to “the fast-moving pace of our industries.” He said this requires The Walt Disney Company (NYSE:DIS) to “constantly assess how to foster a more agile and technologically-enabled workforce to meet tomorrow’s needs.”
The Walt Disney Company (NYSE:DIS) is an American multinational mass media and entertainment conglomerate that operates through 3 core business segments: Disney Entertainment, ESPN, and Disney Experiences.
4. Thermo Fisher Scientific Inc. (NYSE:TMO)
Thermo Fisher Scientific Inc. (NYSE:TMO) is one of the best large-cap stocks to invest in right now. On April 13, TD Cowen reduced its price target on Thermo Fisher Scientific Inc. (NYSE:TMO) from $683 to $625 and kept its Buy rating on the stock.
The research firm raised its Q1 EPS estimate from $5.05 to $5.21 to match the company’s guidance. Thermo Fisher Scientific Inc. (NYSE:TMO) expects 1% organic growth for the first quarter. This guidance includes a 1.8% negative impact due to one less day and a planned customer shutdown.
The firm also noted that the company’s management expressed optimism at TD Cowen’s March conference regarding demand trends for Q1 and 2026. TD Cowen pointed out that operating margins in Q1 are expected to fall compared to the same period last year. The research firm added that Q1 will represent the low point for EPS growth.
TD Cowen sees pharma strength and potential preclinical improvement as key factors that will support organic growth acceleration in the second half of the year.
Thermo Fisher Scientific Inc. (NYSE:TMO) is a leading life science and clinical research company that supplies analytical instruments, clinical development solutions, specialty diagnostics, laboratory, pharmaceutical, and biotechnology services.
3. The Boeing Company (NYSE:BA)
The Boeing Company (NYSE:BA) is one of the best large-cap stocks to invest in right now. On April 16, Reuters reported that The Boeing Company (NYSE:BA) and its unit Millennium Space Systems are working to increase satellite production capacity and develop a new satellite platform to try and meet a growing backlog of orders.
According to the report, The Boeing Company (NYSE:BA) is looking to deliver 26 satellites in 2026, a significant rise from 11 deliveries in 2025. The company is aiming to benefit from the growing reliance on satellite infrastructure in the defense and internet connectivity sectors.
As part of this effort, The Boeing Company’s (NYSE:BA) Resolute, a new mid-class satellite platform, will handle missions that need “more capability than a traditional small satellite can provide, with greater speed and flexibility than a typical large satellite program.”
The Boeing Company (NYSE:BA) stated that it will be investing in integrating its products with those of Millennium Space Systems to increase production. The report by Reuters noted that space-based technologies, from satellite-enabled communications to surveillance, have already been used in recent conflicts, including US strikes in Venezuela and the US-Israeli war on Iran in 2026.
The Boeing Company (NYSE:BA) is a leading global aerospace company that manufactures and services commercial airplanes, defense products, and space systems.
2. Salesforce, Inc. (NYSE:CRM)
Salesforce, Inc. (NYSE:CRM) is one of the best large-cap stocks to invest in right now. On April 16, Truist Securities reiterated its Buy rating on Salesforce, Inc. (NYSE:CRM) with a price target of $280 after the company’s TDX developer conference in San Francisco.
Truist analyst Terry Tillman attended the event and held one-on-one discussions with five customers as well as a subject-matter expert on the Salesforce Flow product. The analyst said that the firm “attended CRM’s TDX developer conference in-person in SF. Below we include highlights from 1:1 convos with 5 customers and a subject-matter expert (SME) on Salesforce Flow product.”
The conversations highlighted suggest that LLM-based agentic coding offerings are not replacing Salesforce, Inc. (NYSE:CRM) and its services. Truist also noted that pricing for Agentforce remains an area where the company has received constructive feedback. At the same time, Salesforce Flow, a no-code automation tool that collects data and performs actions within Salesforce or external systems, has generally been well received.
Truist pointed out that potential Agentforce pricing refinement and continued focus on scaling AI agents could reduce buyer friction and help drive faster adoption in 2026.
Salesforce, Inc. (NYSE:CRM) is a leading American AI cloud-based software company that specializes in customer relationship management (CRM) solutions. The company offers software, tools, services, and applications for sales, customer service, marketing, e-commerce, and analytics.
1. Uber Technologies, Inc. (NYSE:UBER)
Uber Technologies, Inc. (NYSE:UBER) is one of the best large-cap stocks to invest in right now. On April 17, Citizens reiterated its Market Outperform rating on Uber Technologies, Inc. (NYSE:UBER) with a price target of $100 on the stock.
The research firm pointed out that end-to-end models have materially improved the performance of autonomous vehicles (AVs). This is giving AV companies a clear path to move closer to achieving Level 4 (L4) autonomy. Citizens noted that AI has changed how AV models are designed. Better reasoning capabilities are solving edge cases and creating a clearer technical path for vehicles with LiDAR, radar, and camera sensors.
However, Citizens believes that not every company will successfully reach L4 status as financial constraints and execution risks remain key challenges. Additionally, the research firm noted another key issue is solving the “long tail” problem for AVs. However, simulation is helping speed up technical progress in this area.
Citizens noted that this development indicates that Uber Technologies, Inc. (NYSE:UBER) has an increasing number of viable partners as it continues to financially and operationally support the autonomous ecosystem. According to a report by the Financial Times, Uber Technologies, Inc. (NYSE:UBER) plans to invest around $10 billion in AVs, including about $2.5 billion in equity investments and roughly $7.5 billion for robotaxi fleets.
Uber Technologies, Inc. (NYSE:UBER) is a global transportation technology company that focuses on ride-hailing, courier services, food delivery, and freight transport.
While we acknowledge the potential of UBER to grow, our conviction lies in the belief that some AI stocks hold greater promise for delivering higher returns and have limited downside risk. If you are looking for an AI stock that is more promising than UBER and that has 100x upside potential, check out our report about the cheapest AI stock.
READ NEXT: 10 Best Performing AI Stocks to Buy and 10 Unrivaled Stocks of the Next 5 Years.
Disclosure: None.





