5 Best High Volume Penny Stocks to Buy Now

In this article, we will list the 5 Best High Volume Penny Stocks to Buy Now. Please visit 11 Best High Volume Penny Stocks to Buy Now if you would like to see the extended list and the methodology behind it.

5. Fractyl Health, Inc. (NASDAQ:GUTS)

On March 17, 2026, H.C. Wainwright maintained a Buy rating on Fractyl Health, Inc. (NASDAQ:GUTS) with an $8 price target, addressing a sharp selloff following the company’s January data release. The firm said the update triggered a 65% decline in the shares as investors focused on “critical friction points,” including a lack of statistical significance and weight-regain trends. H.C. Wainwright, however, said the results remain consistent with prior Revita data and advised investors to “take a breath,” pointing to a potential pivotal readout in Q4 that could position Revita as a treatment option after GLP-1 therapy discontinuation.

On February 26, 2026, Fractyl Health, Inc. (NASDAQ:GUTS) announced completion of participant randomization in its REMAIN-1 pivotal cohort, a double-blind study evaluating Revita for weight maintenance following GLP-1 discontinuation. CEO Harith Rajagopalan said the milestone marks an “important” step toward generating definitive clinical evidence, noting the study was designed to demonstrate Revita’s effect. Rajagopalan added that prior data and ongoing studies have informed confidence in the program as the company prepares to report topline six-month results in early Q4 2026.

Fractyl Health, Inc. (NASDAQ:GUTS) develops therapies targeting metabolic diseases, including type 2 diabetes and obesity, with its Revita system designed to address duodenal dysfunction.