1. Palisade Bio, Inc. (NASDAQ:PALI)
Number of Hedge Fund Holders: 37
Stock Price as of Last Close on April 10: $1.82
Palisade Bio, Inc. (NASDAQ:PALI) is among the best biotech stocks to buy under $10.
TheFly reported on April 8 that Wolfe Research initiated coverage of PALI with an Outperform rating and a $7 price target. The firm expects limited near-term activity in 2026 but maintains a constructive long-term view. It points to upcoming ulcerative colitis data expected in the second half of 2027 as a key catalyst, noting that the company’s mechanism and internal analyses support a positive outlook despite mixed results seen in similar drug classes. The firm’s view is based on the potential for the program’s clinical profile to differentiate over time as additional data become available.
Earlier on March 30, Palisade Bio, Inc. (NASDAQ:PALI) reported early-stage results from its Phase 1b study of PALI-2108 in patients with fibrostenotic Crohn’s disease. The oral PDE4 prodrug showed a favorable safety profile with no serious adverse events and only mild, self-limiting side effects. Pharmacokinetic findings supported once-daily dosing with adequate systemic and gut tissue exposure, while pharmacodynamic data showed strong target engagement, including increased cAMP levels in ileal tissue and reductions in inflammatory biomarkers such as fecal calprotectin.
Early signals of clinical benefit were observed, including improvements in endoscopic outcomes and measures of intestinal inflammation. Overall results indicate biologic activity across multiple endpoints and support continued development of PALI-2108 as a potential treatment addressing both inflammation and fibrosis in Crohn’s disease.
Palisade Bio, Inc. (NASDAQ:PALI) is a biopharmaceutical company focused on developing therapeutics for gastrointestinal diseases. Its lead programs target conditions such as acute pancreatitis and other serious GI disorders using protease inhibition and anti-inflammatory approaches.
While we acknowledge the risk and potential of PALI as an investment, our conviction lies in the belief that some AI stocks hold greater promise for delivering higher returns and doing so within a shorter time frame. If you are looking for an AI stock that is more promising than PALI and that has 10,000% upside potential, check out our report about this cheapest AI stock.
READ NEXT: 10 Best Mid Cap Stocks to Invest In According to Billionaires and 10 Best Cheap Stocks Under $10 to Buy in April.
Disclosure: None. Insider Monkey focuses on uncovering the best investment ideas of hedge funds and insiders. Please subscribe to our free daily e-newsletter to get the latest investment ideas from hedge funds’ investor letters by entering your email address below.
