13G Filing: RA Capital Management and Derma Sciences, Inc. (DSCI)

UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

SCHEDULE 13G

Under the Securities Exchange Act of
1934

(Amendment No.__)*

Derma Sciences, Inc.

(Name of Issuer)

Common Stock, par value $0.01 per share

(Title of Class of Securities)

249827502

(CUSIP Number)

January 20, 2016

(Date of Event Which Requires Filing of
this Statement)

Check the appropriate box to designate the rule pursuant to
which this Schedule is filed:

[   ] Rule 13d-1(b)

[X] Rule 13d-1(c)

[   ] Rule 13d-1(d)

*The remainder of this cover page shall
be filled out for a reporting person’s initial filing on this form with respect to the subject class of securities, and for
any subsequent amendment containing information which would alter the disclosures provided in a prior cover page.

The information required in the remainder
of this cover page shall not be deemed to be “filed” for the purpose of Section 18 of the Securities Exchange Act of
1934 (“Act”) or otherwise subject to the liabilities of that section of the Act but shall be subject
to all other provisions of the Act (however, see the Notes).

CUSIP No. 249827502

Item 1.

(a) Name of Issuer: Derma Sciences,
Inc. (the “Issuer”).

(b) Address of the Issuer’s
Principal Executive Offices: 214 Carnegie Center, Suite 300, Princeton, NJ 08540.

Item 2.

(a) Name of Person
Filing: This joint statement on Schedule 13G is being filed by Peter Kolchinsky, RA Capital Management, LLC (“Capital”),
and RA Capital Healthcare Fund, L.P. (the “Fund”). Mr. Kolchinsky, Capital and the Fund are collectively referred to
herein as the “Reporting Persons.”

(b) Address of
Principal Business Office: The principal business office of the Reporting Persons is c/o RA Capital Management, LLC, 20 Park
Plaza, Suite 1200, Boston, MA 02116.

(c) Citizenship:
Capital is a Massachusetts limited liability company. The Fund is a Delaware limited partnership. Mr. Kolchinsky is a United States
citizen.

(d) Title and Class
of Securities: Common stock (“Common Stock”)

(e) CUSIP Number:
249827502

Item 3. If this statement is filed
pursuant to §§240.13d-1(b) or 240.13d-2(b) or (c), check whether the person filing is a:

Not applicable.

Item 4. Ownership:

Provide the following information regarding
the aggregate number and percentage of the class of securities of the issuer identified in Item 1.

(a) Amount Beneficially Owned:**

RA Capital Management, LLC – 2,055,676 shares

Peter Kolchinsky – 2,055,676 shares

RA Capital Healthcare Fund, L.P. –
1,613,065 shares

(b) Percent of Class:**

RA Capital Management, LLC – 8.0%

Peter Kolchinsky – 8.0%

RA Capital Healthcare Fund, L.P. –
6.3%

CUSIP No. 249827502

(c) Number of shares as to which such person has:

(i) sole power to
vote or to direct the vote **

RA Capital
Management, LLC – 0 shares

Peter Kolchinsky – 0 shares

RA Capital Healthcare Fund, L.P. – 0 shares

(ii) shared power
to vote or to direct the vote**

RA Capital
Management, LLC – 2,055,676 shares

Peter Kolchinsky – 2,055,676 shares

RA Capital Healthcare Fund, L.P. –
1,613,065 shares

(iii) sole power
to dispose or to direct the disposition of**

RA Capital
Management, LLC – 0 shares

Peter Kolchinsky – 0 shares

RA Capital Healthcare Fund, L.P. – 0 shares

(iv) shared power
to dispose or to direct the disposition of**

RA
Capital Management, LLC – 2,055,676 shares

Peter Kolchinsky – 2,055,676 shares

RA Capital Healthcare Fund, L.P. –
1,613,065 shares

** RA Capital Management, LLC
(“Capital”) is the general partner of RA Capital Healthcare Fund, L.P. (the “Fund”) and serves as investment
adviser for a separately managed account (the “Account”). Peter Kolchinsky is the manager of Capital. Mr. Kolchinsky,
Capital and the Fund are referred to herein collectively as the “Reporting Persons.” As the investment adviser to the
Fund and the Account, Capital may be deemed a beneficial owner, for purposes of Section 13(d) of the Securities Exchange Act of
1934 (the “Act”), of any securities of the Issuer owned by the Fund or the Account. As the manager of Capital, Mr.
Kolchinsky may be deemed a beneficial owner, for purposes of Section 13(d) of the Act, of any securities of the Issuer beneficially
owned by Capital. Capital is a registered investment adviser within the meaning of Rule 13d-1(b)(1)(ii)(E) and Rule 16a-1(a)(v),
and Mr. Kolchinsky is a parent or control person of Capital within the meaning of Rule 13d-1(b)(1)(ii)(G) and Rule 16a-1(a)(1)(vii).
Capital and Mr. Kolchinsky disclaim beneficial ownership of the securities reported in this Schedule 13G Statement (the “Statement”)
other than for the purpose of determining their obligations under Section 13(d) of the Act, and neither the filing of the Statement
nor the filing of this Amendment shall not be deemed an admission that either Capital or Mr. Kolchinsky is or was the beneficial
owner of such securities for any other purpose. In the aggregate, the Reporting Persons have the right to purchase a total of 363,636
shares of Common Stock pursuant to the terms of Common Stock Purchase Warrants issued on June 23, 2011. However, the provisions
of the warrants restrict the exercise of such warrants to the extent that, upon such exercise, the number of shares of Common Stock
then beneficially owned by the holder exceed 9.98% of the total number of shares of the Issuer then outstanding.

CUSIP No. 249827502

Item 5. Ownership of Five Percent
or Less of a Class:

Not applicable.

Item 6. Ownership
of More than Five Percent on Behalf of Another Person:

Not applicable.

Item 7. Identification and Classification
of the Subsidiary Which Acquired the Security Being Reported on By the Parent Holding Company or Control Person:

Not applicable.

Item 8. Identification and Classification
of Members of the Group:

Not applicable.

Item 9. Notice of Dissolution of
Group:

Not applicable.

Item 10. Certification:

By signing below I hereby certify that,
to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of
or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held
in connection with or as a participant in any transaction having that purpose or effect.

CUSIP No. 249827502

SIGNATURE

After reasonable inquiry
and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.

Date: January
29, 2016

RA CAPITAL MANAGEMENT, LLC

By: /s/ Rajeev Shah                     

Rajeev Shah

Authorized Signatory

PETER KOLCHINSKY

/s/ Peter Kolchinsky                    

RA CAPITAL HEALTHCARE FUND, L.P.

By: RA Capital Management, LLC

Its: General Partner

By: /s/ Rajeev Shah                      

Rajeev Shah

Authorized Signatory