13G Filing: Perceptive Advisors and Albireo Pharma Inc. (ALBO)

Albireo Pharma Inc. (NASDAQ:ALBO): Joseph Edelman’s Perceptive Advisors filed an amended 13D.

You can check out Perceptive Advisors’ latest holdings and filings here.

Please follow Perceptive Advisors (if you aren’t already doing so) to get real-time email alerts whenever we publish an article about Perceptive Advisors or update its stock holdings.

Follow Joseph Edelman's Perceptive Advisors

You can access the original SEC filing by clicking here.

Ownership Summary Table

Name Sole Voting Power Shared Voting Power Sole Dispositive Power Shared Dispositive Power Aggregate Amount Owned Power Percent of Class
Perceptive Advisors 0 1,320,000 0 1,320,000 1,320,000 14.8%
Joseph Edelman 0 1,320,000 0 1,320,000 1,320,000 14.8%
Perceptive Life Sciences Master Fund, Ltd 0 1,320,000 0 1,320,000 1,320,000 14.8%

Follow Joseph Edelman's Perceptive Advisors

Page 1 of 8 – SEC Filing

UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

WASHINGTON, D.C. 20549

SCHEDULE 13G

Under the Securities Exchange Act of 1934

(Amendment No. 1)*

Albireo
Pharma, Inc.

(Name of Issuer)

common stock, $0.01 par value per share

(Title of Class of Securities)

01345P 10 6

(CUSIP
Number)

December 1, 2017

(Date of Event Which Requires Filing of this Statement)

Check the
appropriate box to designate the rule pursuant to which this Schedule is filed:

☐ Rule 13d-1(b)

☒ Rule 13d-1(c)


Rule 13d-1(d)

* The remainder of this cover page shall be filled out for a reporting persons initial filing on this form with respect to the subject class of securities, and for any subsequent amendment containing information
which would alter the disclosures provided in a prior cover page.

The information required in the remainder of this cover
page shall not be deemed to be filed for the purpose of Section 18 of the Securities Exchange Act of 1934 (Act) or otherwise subject to the liabilities of that section of the Act but shall be subject to all other
provisions of the Act (however, see the Notes).

Follow Albireo Pharma Inc. (NASDAQ:ALBO)

Page 2 of 8 – SEC Filing


CUSIP No. 01345P 10 6

  1 

NAMES OF
REPORTING PERSONS

Perceptive Advisors LLC

  2

CHECK THE APPROPRIATE BOX IF A MEMBER
OF A GROUP (SEE INSTRUCTIONS)

(a)  ☐        (b)  ☐

  3

SEC USE ONLY

  4

CITIZENSHIP OR PLACE OF
ORGANIZATION

Delaware

NUMBER OF

SHARES

BENEFICIALLY

OWNED BY

EACH

REPORTING

PERSON

WITH:

5                    

SOLE VOTING POWER

0

6

SHARED VOTING POWER

1,320,000

7

SOLE DISPOSITIVE POWER

0

8

SHARED DISPOSITIVE POWER

1,320,000

  9

AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

1,320,000

10

CHECK BOX IF THE AGGREGATE AMOUNT IN
ROW (9) EXCLUDES CERTAIN SHARES (SEE INSTRUCTIONS)  ☐

11

PERCENT OF CLASS REPRESENTED BY AMOUNT
IN ROW 9

14.8%

12

TYPE OF REPORTING PERSON (SEE
INSTRUCTIONS)

IA

Follow Albireo Pharma Inc. (NASDAQ:ALBO)

Page 3 of 8 – SEC Filing


CUSIP No. 01345P 10 6

  1 

NAMES OF
REPORTING PERSONS

Joseph Edelman

  2

CHECK THE APPROPRIATE BOX IF A MEMBER
OF A GROUP (SEE INSTRUCTIONS)

(a)  ☐        (b)  ☐

  3

SEC USE ONLY

  4

CITIZENSHIP OR PLACE OF
ORGANIZATION

United States of America

NUMBER OF

SHARES

BENEFICIALLY

OWNED BY

EACH

REPORTING

PERSON

WITH:

5                    

SOLE VOTING POWER

0

6

SHARED VOTING POWER

1,320,000

7

SOLE DISPOSITIVE POWER

0

8

SHARED DISPOSITIVE POWER

1,320,000

  9

AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

1,320,000

10

CHECK BOX IF THE AGGREGATE AMOUNT IN
ROW (9) EXCLUDES CERTAIN SHARES (SEE INSTRUCTIONS)  ☐

11

PERCENT OF CLASS REPRESENTED BY AMOUNT
IN ROW 9

14.8%

12

TYPE OF REPORTING PERSON (SEE
INSTRUCTIONS)

IN

Follow Albireo Pharma Inc. (NASDAQ:ALBO)

Page 4 of 8 – SEC Filing


CUSIP No. 01345P 10 6

  1 

NAMES OF
REPORTING PERSONS

Perceptive Life Sciences Master Fund, Ltd.

  2

CHECK THE APPROPRIATE BOX IF A MEMBER
OF A GROUP (SEE INSTRUCTIONS)

(a)  ☐        (b)  ☐

  3

SEC USE ONLY

  4

CITIZENSHIP OR PLACE OF
ORGANIZATION

Cayman Islands

NUMBER OF

SHARES

BENEFICIALLY

OWNED BY

EACH

REPORTING

PERSON

WITH:

5                    

SOLE VOTING POWER

0

6

SHARED VOTING POWER

1,320,000

7

SOLE DISPOSITIVE POWER

0

8

SHARED DISPOSITIVE POWER

1,320,000

  9

AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

1,320,000

10

CHECK BOX IF THE AGGREGATE AMOUNT IN
ROW (9) EXCLUDES CERTAIN SHARES (SEE INSTRUCTIONS)  ☐

11

PERCENT OF CLASS REPRESENTED BY AMOUNT
IN ROW 9

14.8%

12

TYPE OF REPORTING PERSON (SEE
INSTRUCTIONS)

CO

Follow Albireo Pharma Inc. (NASDAQ:ALBO)

Page 5 of 8 – SEC Filing


Item 1(a). Name of Issuer:

Albireo Pharma, Inc. (the Issuer)

Item 1(b). Address of Issuers Principal Executive Offices:

10 Post Office Square,
Suite 502 South

Boston, Massachusetts 02109

Item 2(a). Names of Persons Filing:

The names of the persons filing this report
(collectively, the Reporting Persons) are:

Perceptive Advisors LLC (Perceptive Advisors)

Joseph Edelman (Mr. Edelman)

Perceptive Life Sciences Master Fund, Ltd. (the Master Fund)

Item 2(b). Address of Principal Business Office or, if None, Residence:

The address of the
principal business office of each of the Reporting Persons is:

51 Astor Place, 10th Floor

New York, NY 10003

Item 2(c). Citizenship:

Perceptive Advisors is a Delaware limited liability company

Mr. Edelman is a United States citizen

The Master Fund is a Cayman Islands corporation

Item 2(d). Title of Class of Securities:

common stock, $0.01 par value per share
(Common Stock)

Item 2(e). CUSIP Number:

01345P 10 6

Item 3. If this statement is filed pursuant to §§ 240.13d-1(b) or 240.13d-2(b) or (c), check whether the person filing is a:

Not applicable.

Item 4. Ownership.

The information required by this item with respect to each Reporting
Person is set forth in Rows 5 through 9 and 11 of the cover page to this Schedule 13G. The ownership percentages reported are based on 8,899,451 outstanding shares of Common Stock, as reported in the Issuers Form 10-Q filed on
November 14, 2017.

Follow Albireo Pharma Inc. (NASDAQ:ALBO)

Page 6 of 8 – SEC Filing


The Master Fund directly holds 1,320,000 shares of Common Stock. Perceptive Advisors serves as
the investment manager to the Master Fund and may be deemed to beneficially own the securities directly held by the Master Fund. Mr. Edelman is the managing member of Perceptive Advisors and may be deemed to beneficially own the securities
directly held by the Master Fund.

Item 5. Ownership of Five Percent or Less of a Class.

If this statement is being filed
to report the fact that as of the date hereof the Reporting Persons have ceased to be the beneficial owner of more than five percent of the class of securities, check the following ☐.

Item 6. Ownership of More than Five Percent on Behalf of Another Person.

Not
applicable.

Item 7. Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on by the Parent Holding Company or Control Person.

Not applicable.

Item 8. Identification and Classification of Members of the Group.

Not applicable.

Item 9. Notice of Dissolution of Group.

Not applicable.

Item 10. Certification.

By signing below I certify that, to the best of my knowledge and
belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as
a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under § 240.14a-11.

Follow Albireo Pharma Inc. (NASDAQ:ALBO)

Page 7 of 8 – SEC Filing


SIGNATURE

After reasonable inquiry and to the best of its knowledge and belief, each of the undersigned certifies that the information set forth in this
statement is true, complete and correct.

Date: December 4, 2017
PERCEPTIVE ADVISORS LLC
By:

/s/ Joseph Edelman

Name:  Joseph Edelman

Title:    Managing Member

/s/ Joseph Edelman

JOSEPH EDELMAN
PERCEPTIVE LIFE SCIENCES MASTER FUND, LTD.
By: Perceptive Advisors LLC
By:

/s/ Joseph Edelman

Name:  Joseph Edelman

Title:    Managing Member

Follow Albireo Pharma Inc. (NASDAQ:ALBO)

Page 8 of 8 – SEC Filing


EXHIBIT 1

AGREEMENT

The persons below hereby agree that
the Schedule 13G to which this agreement is attached as an exhibit, as well as all future amendments to such Schedule 13G, shall be filed on behalf of each of them. This agreement is intended to satisfy the requirements of Rule 13d-1(k)(1)(iii)
under the Securities Exchange Act of 1934.

Date: December 4, 2017
PERCEPTIVE ADVISORS LLC
By:

/s/ Joseph Edelman

Name:  Joseph Edelman

Title:    Managing Member

/s/ Joseph Edelman

JOSEPH EDELMAN
PERCEPTIVE LIFE SCIENCES MASTER FUND, LTD.
By: Perceptive Advisors LLC
By:

/s/ Joseph Edelman

Name:  Joseph Edelman

Title:    Managing Member

Follow Albireo Pharma Inc. (NASDAQ:ALBO)