13G Filing: Palo Alto Investors and Epizyme Inc. (NASDAQ:EPZM)

Page 2 of 8 – SEC Filing

1. Names of Reporting Persons.

Patrick Lee, MD

2. Check the Appropriate Box if
a Member of a Group (See Instructions)

(a)

(b) ___X___

3. SEC Use Only

4. Citizenship or Place of Organization
U.S.A.

Number of

Shares

Beneficially

Owned by

Each Reporting

Person With:

5. Sole Voting Power 0
6. Shared Voting Power 4,699,675
7. Sole Dispositive Power 0
8. Shared Dispositive Power 4,699,675

9. Aggregate Amount Beneficially
Owned by Each Reporting Person 4,699,675

10. Check if the Aggregate Amount
in Row (9) Excludes Certain Shares (See
Instructions) ______

11. Percent of Class Represented
by Amount in Row (9) 8.07%

12. Type of Reporting Person (See
Instructions) IN, HC

2
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