Page 2 of 10 – SEC Filing
| CUSIP No. 14888U101 | 13G | Page 2 of 9 Pages |
| 1. | NAMES OF REPORTING PERSONS Great Point Partners, LLC I.R.S. IDENTIFICATION NO. OF ABOVE PERSON (ENTITIES ONLY): 37-1475292 | |
| 2. | CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP | |
| (a) | o | |
| (b) | o | |
| 3. | SEC USE ONLY | |
| 4. | CITIZENSHIP OR PLACE OF ORGANIZATION USA | |
| NUMBER OF SHARES BENEFICIALLY OWNED BY EACH REPORTING PERSON WITH | 5. | SOLE VOTING POWER | |
| 0 | |||
| 6. | SHARED VOTING POWER | ||
| 5,262,346 | |||
| 7. | SOLE DISPOSITIVE POWER | ||
| 0 | |||
| 8. | SHARED DISPOSITIVE POWER | ||
| 5,262,346 |
| 9. | AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON | |
| 5,262,346 | ||
| 10. | CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES (See Instructions) | o |
| 11. | PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9) | |
| 5.14%1 | ||
| 12. | TYPE OF REPORTING PERSON (See Instructions) |
| IA |
| 1 | Based on a total of 102,474,498 shares outstanding, as reported in the Issuer’s Form 424B5 Prospectus filed with the SEC on November 28, 2017 (such share number inclusive of the underwriters’ exercise of their option to purchase additional shares in full as referenced therein). |
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