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Ownership Summary Table
|Name||Sole Voting Power||Shared Voting Power||Sole Dispositive Power||Shared Dispositive Power||Aggregate Amount Owned Power||Percent of Class|
|Deerfield Private Design Fund||0||100,515||0||100,515||100,515||0.72%|
|Deerfield Special Situations Fund||0||281,184||0||281,184||281,184||2.03%|
|Deerfield Private Design International||0||161,788||0||161,788||161,788||1.17%|
|Deerfield Private Design Fund II||0||181,560||0||181,560||181,560||1.31%|
|Deerfield Private Design International II||0||208,053||0||208,053||208,053||1.50%|
|Deerfield Management Company||0||936,175||0||936,175||936,175||6.74%|
|James E. Flynn||0||936,175||0||936,175||936,175||6.74%|
Page 1 of 13 – SEC Filing
AND EXCHANGE COMMISSION
INFORMATION TO BE INCLUDED IN STATEMENTS FILED PURSUANT TO §
21.16d-1(a) AND AMENDMENTS THERETO FILED PURSUANT TO § 240.13D-2(a)
(Amendment No. 4)*
of Class of Securities)
With a copy to:
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of Event which Requires Filing of this Statement)
If the filing person
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filed in paper format shall include a signed original and five copies of the schedule, including all exhibits. See § 240.13d-7
for other parties to whom copies are to be sent.
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(Page 1 of 13 Pages)
* The remainder of this cover page shall be filled out for a
reporting person’s initial filing on this form with respect to the subject class of securities, and for any subsequent amendment
containing information which would alter disclosures provided in a prior cover page.
The information required on the remainder of this cover page
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or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however,
see the Notes).