13 Hot Stocks to Buy with the Highest Upside Potential

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11. Crinetics Pharmaceuticals Inc. (NASDAQ:CRNX)

Potential Upside: 67.36%

Number of Hedge Fund Holders: 31

Crinetics Pharmaceuticals Inc. (NASDAQ:CRNX) is one of the 13 hot stocks to buy with the highest upside potential. On January 30, Stifel raised its price target on Crinetics Pharmaceuticals Inc. (NASDAQ:CRNX) to $84 from $75, while maintaining its Buy rating, noting that the company’s pre-report for the fourth quarter of 2025 went better than early investor expectations for the first quarter of the launch of Palsonify, an FDA-approved, once-daily oral medication for treating adults with acromegaly.

Meanwhile, in a January 23 report, Yasmeen Rahimi from Piper Sandler maintained a Buy rating on Crinetics Pharmaceuticals Inc. (NASDAQ:CRNX) with a price target of $97. Earlier in the month, on January 12, Goldman Sachs upgraded its stock rating on Crinetics Pharmaceuticals Inc. (NASDAQ:CRNX) to Buy from Neutral, with a $67 price target, citing positive Phase 2 clinical trial results for the company’s congenital adrenal hyperplasia treatment. The analyst noted that 25% of patients in Cohort 4 of its Phase 2 TouCAHn study have already achieved the primary composite endpoint planned for the Phase 3 trial, which the firm believes has “highly derisked” the upcoming late-stage study’s novel endpoint design.

Crinetics Pharmaceuticals Inc. (NASDAQ:CRNX) operates as a clinical-stage pharmaceutical company focused on the discovery, development, and commercialization of novel therapeutics for rare endocrine diseases and endocrine-related tumors.

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