12 Most Profitable Large Cap Stocks to Buy Right Now

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9. Booking Holdings Inc. (NASDAQ:BKNG)

Market Capitalization as of November 21: $153.69 billion

TTM Net Income as of November 21: $5.04 billion

TTM Net Income Margin as of November 21: 19.37%

Number of Hedge Fund Holders: 92

Average Upside Potential as of November 21: 31.08%

Booking Holdings Inc. (NASDAQ:BKNG) is one of the most profitable large cap stocks to buy right now. On November 13, Wedbush upgraded Booking Holding to Outperform from Neutral, while setting a price target of $6,000. The firm reported that Booking Holdings experienced healthy global travel demand during Q3 2025, which met expectations. Wedbush noted that the company is recognized as the best-positioned Online Travel Agency globally due to its global scale and diversification, robust liquidity, and free cash flow conversion, and successful executions across major strategic initiatives.

The firm’s strong operational health was reflected in the results across key metrics and segments reported for Q3. In its quarterly earnings call, Booking Holdings reported achieving $50 billion in Gross Bookings, which was a 14% year-over-year increase. Revenue for the quarter was $9.0 billion, growing 13%. This top-line performance drove profitability, with Adjusted EBITDA reaching $4.2 billion, an increase of 15% year-over-year. Adjusted EPS also saw a 19% surge to $99.50 per share.

The company noted that its Genius loyalty program and advancements in AI (like AI-powered chatbots and Smart Messenger) acted as key differentiators that enhanced both customer and partner experiences.

Booking Holdings Inc. (NASDAQ:BKNG) provides online and traditional travel and restaurant reservations and related services in the US, the Netherlands, and internationally.

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