12 Low Priced Stocks to Buy with High Upside Potential

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1. Ocular Therapeutix Inc. (NASDAQ:OCUL)

Market Capitalization as of December 26: $2.68 billion

Share Price as of December 26: $12.56

Number of Hedge Fund Holders: 44

Average Upside Potential as of December 26: 91.08%

Ocular Therapeutix Inc. (NASDAQ:OCUL) is one of the low priced stocks to buy with high upside potential. On December 12, Bank of America raised the firm’s price target on Ocular Therapeutix to $21 from $18 and maintained a Buy rating on the shares. After hosting CEO Pravin Dugel to review upcoming corporate milestones, the firm highlighted the development strategy for AXPAXLI, supported by pivotal trials in both wet AMD and diabetic retinopathy. BofA remains optimistic about the drug’s unique competitive advantages and the possibility of a faster regulatory path.

On December 8, Ocular Therapeutix Inc. (NASDAQ:OCUL) announced a major acceleration of its regulatory strategy for AXPAXLI (OTX-TKI), which is an investigational treatment for wet age-related macular degeneration (wet AMD). The company now plans to submit an NDA shortly after receiving one-year data from its SOL-1 Phase 3 trial, provided the results are positive. These topline results remain on track for release in Q1 2026.

The accelerated timeline is supported by recent FDA guidance suggesting that a single, well-powered registrational trial may suffice for approval, rather than the traditional requirement of two studies. Ocular Therapeutix Inc. (NASDAQ:OCUL) believes SOL-1 meets these high standards because it is a superiority trial and is conducted under a Special Protocol Assessment agreement. The SOL-1 study itself completed randomization in December 2024 with 344 treatment-naïve subjects. It compares AXPAXLI against a 2 mg dose of aflibercept, with a primary endpoint measuring the proportion of patients who maintain visual acuity at week 36.

Ocular Therapeutix Inc. (NASDAQ:OCUL) is a biopharmaceutical company that develops and commercializes therapies for retinal diseases and other eye conditions using its bioresorbable hydrogel-based formulation technology in the US.

While we acknowledge the potential of OCUL to grow, our conviction lies in the belief that some AI stocks hold greater promise for delivering higher returns and have limited downside risk. If you are looking for an AI stock that is more promising than OCUL and that has 100x upside potential, check out our report about this cheapest AI stock.

READ NEXT: 30 Stocks That Should Double in 3 Years and 11 Hidden AI Stocks to Buy Right Now.

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