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12 Hot Penny Stocks to Invest in Right Now

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In this piece, we will discuss the 12 hot penny stocks to invest in right now.

Amid an uncertain macro environment, where the economic outlook is blurry, the momentum of penny stocks depends heavily on shifting market psychology rather than macro certainty.

Goldman Sachs Asset Management portfolio manager Greg Tuorto appeared on CNBC on November 17, 2025. Despite the uncertainty around the timing of rate cuts, he noted that small-cap stocks are quietly building their own momentum. The small-cap segment is attracting renewed attention following strong third-quarter earnings from smaller companies, making it more appealing than large caps.

Furthermore, he highlighted several catalysts that he said are driving investor interest in early-stage small-cap stocks. These catalysts include heightened strategic M&A activity, renewed activity in biotech, an improving IPO environment, and new opportunities in semiconductor, defense, and energy-infrastructure stocks linked to the expanding AI ecosystem. He believes these factors are highly relevant to investors looking at small-cap stocks because those small-cap companies would be ones to see significant upside from sector-specific upswings, especially in AI-linked industries.

Meanwhile, the Russell 2000 index is up 21.60% over the past six months. However, in the last week, the index fell for a fourth straight week. This marks its longest run of weekly losses since March.

With Tuorto emphasizing the market is “broadening out,” let’s quickly look at our list of 12 hot penny stocks to buy.

Image: Depositphotos

Our Methodology

To curate our list of the 12 hot penny stocks to invest in right now, we relied on the financial media sources, ETFs, and stock screeners to compile a list of penny stocks (share price under $5) with the last three month share price returns of over 50% and an upside potential of over 20% as of November 24, 2025. Next, we selected the top 12 stocks with the highest potential upside and ranked them in ascending order. We also considered hedge fund sentiment toward these stocks using Insider Monkey’s hedge fund database, which tracks 983 hedge funds as of Q2 2025.

Why are we interested in the stocks that hedge funds pile into? The reason is simple: our research has shown that we can outperform the market by imitating the top stock picks of the best hedge funds. Our quarterly newsletter’s strategy selects 14 small-cap and large-cap stocks every quarter and has returned 427.7% since May 2014, beating its benchmark by 264 percentage points (see more details here).

12 Hot Penny Stocks to Invest in Right Now

12. Shattuck Labs, Inc. (NASDAQ:STTK)

3-Month Performance as of November 25: 102.21%

Average Upside Potential as of November 24: 45.63%

Number of Hedge Fund Holders: 13

With strong three-month performance and significant upside potential, Shattuck Labs, Inc. (NASDAQ:STTK) secures a spot on our list of the 12 hot penny stocks to invest in right now.

Highlighting the SL-325’s Phase 1 readout, expected in Q2 2026, H.C. Wainwright’s Joseph Pantginis reiterated a “Hold” rating on Shattuck Labs, Inc. (NASDAQ:STTK) on November 7, 2025. The analyst believes the drug holds significant clinical potential, boosting the analyst’s confidence. The drug remains a key growth catalyst, with DR3-based bispecific antibodies expected to provide longer-term upside. Pantginis also cited the company’s solid financial position as visible through its cash and investments balance of $86.10 million. Thus, the analyst sees a balanced risk profile for the company, with SL-325 remaining central to the investment case.

Meanwhile, Shattuck Labs, Inc. (NASDAQ:STTK) announced its third-quarter 2025 results on November 6, 2025. The company, still in its development stage, noted R&D declining to $7.60 million, while G&A expenses totaled $4.10 million. Reflecting disciplined execution, Shattuck Labs reaffirmed advancement of the Phase 1 SL-325 trial. It also reported continued progress toward selecting a bispecific candidate in 2026. With a healthy cash balance, the company looks well-positioned to advance the drug into Phase 2 trials. Net loss for the quarter was $10.1 million, or $0.14 per basic and diluted share.

Shattuck Labs, Inc. (NASDAQ:STTK) focuses on developing novel therapies for autoimmune and inflammatory diseases. Its SL-325 drug aims for a complete blockade of the validated DR3/TL1A pathway.

11. Erasca, Inc. (NASDAQ:ERAS)

3-Month Performance as of November 25: 93.08%

Average Upside Potential as of November 24: 73.01%

Number of Hedge Fund Holders: 25

Erasca, Inc. (NASDAQ:ERAS) is one of the 12 hot penny stocks to invest in right now.

On November 14, 2025, Erasca, Inc. (NASDAQ:ERAS) saw Guggenheim’s analyst Michael Schmidt reiterate a “Buy” rating with a $5 price target, following the company’s Q3 2025 results. The analyst highlighted key drivers, including recent Phase 1 trial initiations, additional validation from peer programs, and growing investor anticipation ahead of the first clinical data disclosures in 2025.

A day earlier, on November 12, 2025, Erasca, Inc. (NASDAQ:ERAS) reported its third-quarter 2025 results, posting a net loss of $30.6 million, or $0.11 per share. The company closed the quarter with a solid cash position of $362.4 million, providing a runway into 2028. The company noted a decline in R&D expenses due to a reduction in costs related to clinical trials, preclinical studies, and discovery activities.

Erasca, Inc. (NASDAQ:ERAS) has attracted greater analyst confidence with its progress across multiple programs, including the recent U.S. patent issuance for ERAS-0015 and the ongoing development of ERAS-4001. Positioned as a potential best-in-class therapy, the two developments reflect the company’s strengthening intellectual property portfolio and reinforce expectations around upcoming 2026 Phase 1 monotherapy readouts.

Looking ahead, Erasca, Inc. (NASDAQ:ERAS)’s management remains confident in its long-term growth, thanks to the pending clinical milestones, strengthened scientific leadership, and a robust patent estate.

Erasca, Inc. (NASDAQ:ERAS), a clinical-stage precision oncology company, develops therapies targeting the RAS/MAPK pathway.

10. CytomX Therapeutics, Inc. (NASDAQ:CTMX)

3-Month Performance as of November 25: 107.50%

Average Upside Potential as of November 24: 78.09%

Number of Hedge Fund Holders: 21

With strong three-month performance and significant upside potential, CytomX Therapeutics, Inc. (NASDAQ:CTMX) secures a spot on our list of the 12 hot penny stocks to invest in right now.

The Fly reported on November 11, 2025, that CytomX Therapeutics, Inc. (NASDAQ:CTMX)’s price target was raised from $5 to $10 by H.C. Wainwright’s Mitchell Kapoor. Reiterating a “Buy” rating, the analyst highlighted strong demand for the CX-2051 Phase 1 program. With Phase 1 study enrollment projected to reach approximately 100 patients by Q1 2026, the program’s data package is expected to strengthen, supporting a potential approval pathway.

Meanwhile, CytomX Therapeutics, Inc. (NASDAQ:CTMX) reported its Q3 2025 results on November 6, 2025. The quarter saw a reduction in revenue to $6 million from $33.4 million in Q3 2024. The revenue decline reflected the completion of certain collaboration obligations. However, operating expenses, which fell to $21.7 million, reflected the company’s continued operating discipline.

The quarter also marked significant pipeline progress, including a robust CX-2051 Phase 1 expansion and preparations for a data update in Q1 2026. Management expressed confidence while emphasizing ongoing CX-801 development, including upcoming biomarker data at SITC 2025 Annual Meeting and continued dose escalation in combination with KEYTRUDA. CytomX Therapeutics, Inc. (NASDAQ:CTMX) closed the quarter with $143.6 million in cash balances, supporting operations until Q2 2027.

CytomX Therapeutics, Inc. (NASDAQ:CTMX), an oncology-focused biopharmaceutical company, develops conditionally activated, tumor-localized biologics using its PROBODY platform.

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The $250 Trillion AI Hype is Real. A few years from now, you’ll probably wish you’d bought this stock.

When Jeff Bezos said that one breakthrough technology would shape Amazon’s destiny, even Wall Street’s biggest analysts were caught off guard.

Fast forward a year and Amazon’s new CEO Andy Jassy described generative AI as a “once-in-a-lifetime” technology that is already being used across Amazon to reinvent customer experiences.

At the 8th Future Investment Initiative conference, Elon Musk predicted that by 2040 there would be at least 10 billion humanoid robots, with each priced between $20,000 and $25,000.

Do the math. According to Musk, this technology could be worth $250 trillion by 2040.

Put another way, that’s roughly equal to:

  • 175 Teslas
  • 107 Amazons
  • 140 Metas
  • 84 Googles
  • 65 Microsofts
  • And 55 Nvidias

And here’s the wild part — this $250 trillion wave isn’t tied to one company, but to an entire ecosystem of AI innovators set to reshape the global economy.

It’s a leap so massive, it could reshape how businesses, governments, and consumers operate worldwide.

Even if that $250 trillion figure sounds ambitious, major firms like PwC and McKinsey still see AI unlocking multi-trillion-dollar potential.

How could anything be worth that much?

The answer lies in a breakthrough so powerful it’s redefining how humanity works, learns, and creates.

And this breakthrough has already set off a frenzy among hedge funds and Wall Street’s top investors.

What most investors don’t realize is that one under-owned company holds the key to this $250 trillion revolution.

In fact, Verge argues this company’s supercheap AI technology should concern rivals.

Before I reveal the details, let’s talk about how some of the richest people on the planet are positioning themselves.

  • Bill Gates sees artificial intelligence as the “biggest technological advance in my lifetime,” more transformative than the internet or personal computer, capable of improving healthcare, education, and addressing climate change.
  • Larry Ellison — through Oracle, is spending billions on Nvidia chips and partnering with Cohere to embed generative AI across Oracle’s cloud and apps.
  • Warren Buffett — not known for tech hype — says this breakthrough could have a ‘hugely beneficial social impact.

When billionaires from Silicon Valley to Wall Street line up behind the same idea — you know it’s worth paying attention to.

Even as we admire what Tesla, Nvidia, Alphabet, and Microsoft have built, we believe an even greater opportunity lies elsewhere…

But the real story isn’t Nvidia — it’s a much smaller company quietly improving the critical technology that makes this entire revolution possible.

And judging by what I’m hearing from both Silicon Valley insiders and Wall Street veterans…

This prediction might not be bold at all:

A few years from now, you’ll wish you’d owned this stock.

The best part? You can discover everything about this company and its groundbreaking technology right now.

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Trust me — you’ll want to read this report before putting another dollar into any tech stock.

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If you’re thinking about getting in, don’t wait – because once Wall Street catches wind of this story, the easy money will be gone.

Space is Limited! Only 1000 spots are available for this exclusive offer. Don’t let this chance slip away – subscribe to our Premium Readership Newsletter today and unlock the potential for a life-changing investment.

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1. Head over to our website and subscribe to our Premium Readership Newsletter for just $9.99 a month.

2. Enjoy a year of ad-free browsing, exclusive access to our in-depth report on the revolutionary AI company, and the upcoming issues of our Premium Readership Newsletter over the next 12 months.

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AI, Tariffs, Nuclear Power: One Undervalued Stock Connects ALL the Dots (Before It Explodes!)

Artificial intelligence is the greatest investment opportunity of our lifetime. The time to invest in groundbreaking AI is now, and this stock is a steal!

AI is eating the world—and the machines behind it are ravenous.

Each ChatGPT query, each model update, each robotic breakthrough consumes massive amounts of energy. In fact, AI is already pushing global power grids to the brink.

Wall Street is pouring hundreds of billions into artificial intelligence—training smarter chatbots, automating industries, and building the digital future. But there’s one urgent question few are asking:

Where will all of that energy come from?

AI is the most electricity-hungry technology ever invented. Each data center powering large language models like ChatGPT consumes as much energy as a small city. And it’s about to get worse.

Even Sam Altman, the founder of OpenAI, issued a stark warning:

“The future of AI depends on an energy breakthrough.”

Elon Musk was even more blunt:

“AI will run out of electricity by next year.”

As the world chases faster, smarter machines, a hidden crisis is emerging behind the scenes. Power grids are strained. Electricity prices are rising. Utilities are scrambling to expand capacity.

And that’s where the real opportunity lies…

One little-known company—almost entirely overlooked by most AI investors—could be the ultimate backdoor play. It’s not a chipmaker. It’s not a cloud platform. But it might be the most important AI stock in the US owns critical energy infrastructure assets positioned to feed the coming AI energy spike.

As demand from AI data centers explodes, this company is gearing up to profit from the most valuable commodity in the digital age: electricity.

The “Toll Booth” Operator of the AI Energy Boom

  • It owns critical nuclear energy infrastructure assets, positioning it at the heart of America’s next-generation power strategy.
  • It’s one of the only global companies capable of executing large-scale, complex EPC (engineering, procurement, and construction) projects across oil, gas, renewable fuels, and industrial infrastructure.
  • It plays a pivotal role in U.S. LNG exportation—a sector about to explode under President Trump’s renewed “America First” energy doctrine.

Trump has made it clear: Europe and U.S. allies must buy American LNG.

And our company sits in the toll booth—collecting fees on every drop exported.

But that’s not all…

As Trump’s proposed tariffs push American manufacturers to bring their operations back home, this company will be first in line to rebuild, retrofit, and reengineer those facilities.

AI. Energy. Tariffs. Onshoring. This One Company Ties It All Together.

While the world is distracted by flashy AI tickers, a few smart investors are quietly scooping up shares of the one company powering it all from behind the scenes.

AI needs energy. Energy needs infrastructure.

And infrastructure needs a builder with experience, scale, and execution.

This company has its finger in every pie—and Wall Street is just starting to notice.

Wall Street is noticing this company also because it is quietly riding all of these tailwinds—without the sky-high valuation.

While most energy and utility firms are buried under mountains of debt and coughing up hefty interest payments just to appease bondholders…

This company is completely debt-free.

In fact, it’s sitting on a war chest of cash—equal to nearly one-third of its entire market cap.

It also owns a huge equity stake in another red-hot AI play, giving investors indirect exposure to multiple AI growth engines without paying a premium.

And here’s what the smart money has started whispering…

The Hedge Fund Secret That’s Starting to Leak Out

This stock is so off-the-radar, so absurdly undervalued, that some of the most secretive hedge fund managers in the world have begun pitching it at closed-door investment summits.

They’re sharing it quietly, away from the cameras, to rooms full of ultra-wealthy clients.

Why? Because excluding cash and investments, this company is trading at less than 7 times earnings.

And that’s for a business tied to:

  • The AI infrastructure supercycle
  • The onshoring boom driven by Trump-era tariffs
  • A surge in U.S. LNG exports
  • And a unique footprint in nuclear energy—the future of clean, reliable power

You simply won’t find another AI and energy stock this cheap… with this much upside.

This isn’t a hype stock. It’s not riding on hope.

It’s delivering real cash flows, owns critical infrastructure, and holds stakes in other major growth stories.

This is your chance to get in before the rockets take off!

Disruption is the New Name of the Game: Let’s face it, complacency breeds stagnation.

AI is the ultimate disruptor, and it’s shaking the foundations of traditional industries.

The companies that embrace AI will thrive, while the dinosaurs clinging to outdated methods will be left in the dust.

As an investor, you want to be on the side of the winners, and AI is the winning ticket.

The Talent Pool is Overflowing: The world’s brightest minds are flocking to AI.

From computer scientists to mathematicians, the next generation of innovators is pouring its energy into this field.

This influx of talent guarantees a constant stream of groundbreaking ideas and rapid advancements.

By investing in AI, you’re essentially backing the future.

The future is powered by artificial intelligence, and the time to invest is NOW.

Don’t be a spectator in this technological revolution.

Dive into the AI gold rush and watch your portfolio soar alongside the brightest minds of our generation.

This isn’t just about making money – it’s about being part of the future.

So, buckle up and get ready for the ride of your investment life!

Act Now and Unlock a Potential 100+% Return within 12 to 24 months.

We’re now offering month-to-month subscriptions with no commitments.

For a ridiculously low price of just $9.99 per month, you can unlock our in-depth investment research and exclusive insights – that’s less than a single fast food meal!

Space is Limited! Only 1000 spots are available for this exclusive offer. Don’t let this chance slip away – subscribe to our Premium Readership Newsletter today and unlock the potential for a life-changing investment.

Here’s what to do next:

1. Head over to our website and subscribe to our Premium Readership Newsletter for just $9.99.

2. Enjoy a month of ad-free browsing, exclusive access to our in-depth report on the Trump tariff and nuclear energy company as well as the revolutionary AI-robotics company, and the upcoming issues of our Premium Readership Newsletter.

3. Sit back, relax, and know that you’re backed by our ironclad 30-day money-back guarantee.

Don’t miss out on this incredible opportunity! Subscribe now and take control of your AI investment future!


No worries about auto-renewals! Our 30-Day Money-Back Guarantee applies whether you’re joining us for the first time or renewing your subscription a month later!