12 Best Mid-Cap Stocks with Huge Upside Potential

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2. Revolution Medicines, Inc. (NASDAQ:RVMD)

Analyst Upside: 82.14%

Market Capitalization: $7.10 billion

Number of Hedge Fund Holders: 71

Revolution Medicines, Inc. (NASDAQ:RVMD) ranks among the best mid-cap stocks with huge upside potential. Oppenheimer reaffirmed its Outperform rating and $75 price target for Revolution Medicines, Inc. (NASDAQ:RVMD) on August 25 after speaking with company management during a West Coast Biotech Bus Tour. The firm highlighted that Revolution recently stated that the initial results from the daraxonrasib RASolute-302 study would be available in 2026, with enrollment continuing smoothly.

As previously disclosed, Revolution Medicines, Inc. (NASDAQ:RVMD) indicated that additional Phase 3 trials of daraxonrasib in adjuvant and first-line pancreatic ductal adenocarcinoma (PDAC) remain scheduled to start this year.

Oppenheimer emphasized that although the filing of daraxonrasib in second-line PDAC may take place in 2026, Revolution Medicines, Inc. (NASDAQ:RVMD) continues to make strides in all areas of its business, and its improved cash sheet is enabling both possible commercialization and continued clinical development.

Revolution Medicines, Inc. (NASDAQ:RVMD) is a clinical-stage biotech company that develops cancer medications that target RAS, a major category of genetic abnormalities that are frequently present in difficult-to-treat cancers.

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