11 Best Short-Term Stocks to Invest in

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1. Olema Pharmaceuticals, Inc. (NASDAQ:OLMA)

Performance 1 Year: -67.38%

Olema Pharmaceuticals, Inc. (NASDAQ:OLMA) holds a spot among our list of 11 best short-term stocks to invest in. The company sees its Buy rating reiterated following promising results from its clinical trials, including the VERITAC-2 trial.

Headquartered in California, Olema Pharmaceuticals, Inc. (NASDAQ:OLMA) is a clinical-stage biopharmaceutical company focused on discovering, developing, and commercializing therapies for women’s cancers. Its lead product candidate, palazestrant (OP-1250), is an estrogen receptor (ER) antagonist and degrader being evaluated in clinical trials for breast cancer. The company also has another drug candidate, OP-3136, a KAT6 inhibitor, in Phase 1 clinical trials.

In its Q1 earnings report, released on May 13, 2025, the company announced that the OPERA-02 trial for palazestrant and ribociclib in breast cancer is on track for initiation in 2025. The OPERA-01 monotherapy trial also continues, with results expected in 2026. Olema Pharmaceuticals, Inc. (NASDAQ:OLMA) has further promising results in clinical data for OP-3136 in multiple cancer types.

Additionally, the company’s trials on VERITAC-2 showed that the drug is more effective for metastatic breast cancer with ESR1 mutations, as it improves survival with a good safety profile. Following these developments, H.C. Wainwright reiterated the Buy rating on the stock while maintaining the price target of $28.00.

Olema Pharmaceuticals, Inc. (NASDAQ:OLMA) is showing a potential short-term rebound, gaining 7.19% this week despite a decline of 67.38% over the past year, attracting the interest of short-term investors.

While we acknowledge the potential of OLMA to grow, our conviction lies in the belief that some AI stocks hold greater promise for delivering higher returns and have limited downside risk. If you are looking for an AI stock that is more promising than OLMA and that has 100x upside potential, check out our report about this cheapest AI stock.

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