10 Unstoppable Stocks to Buy and Hold for the Next 3 Years

7. Alnylam Pharmaceuticals, Inc. (NASDAQ:ALNY)

Alnylam Pharmaceuticals, Inc. (NASDAQ:ALNY) is one of the Unstoppable Stocks to Buy and Hold for the Next 3 Years. On February 17, analyst Whitney Ijem from Canaccord Genuity maintained a “Buy” rating on the company’s stock with a price objective of $429.00. The analyst’s rating is supported by the factors related to Alnylam Pharmaceuticals, Inc. (NASDAQ:ALNY)’s execution and growth outlook.

The analyst noted that the roll-out of AMVUTTRA in transthyretin-mediated amyloidosis continues to outperform initial expectations. The current sales are approximately double of what the broader market expected at the time of approval. Also, Alnylam Pharmaceuticals, Inc. (NASDAQ:ALNY)’s company guidance reflected continued robust expansion of top-line into 2026.

In a different release, Alnylam Pharmaceuticals, Inc. (NASDAQ:ALNY) released its consolidated financial results for Q4 2025 and FY 2025. The company highlighted approval of AMVUTTRA for ATTR-CM in the U.S., fueling its total net product revenues of ~$3 billion, or 81% YoY growth.

Alnylam Pharmaceuticals, Inc. (NASDAQ:ALNY) is a global biopharmaceutical company and the pioneer of the RNA interference (RNAi) revolution.