10 Most Profitable S&P 500 Stocks to Buy Now

7. CSX Corporation (NASDAQ:CSX)

On March 19, 2026, Evercore ISI downgraded CSX Corporation (NASDAQ:CSX) to In Line from Outperform and raised its price target to $41 from $40. Evercore said that while the company could still deliver industry-leading EPS growth over the next two years, much of the upside appears already reflected in the stock following a 51% rebound from its 52-week low and a 9.35% gain year-to-date.

On March 16, 2026, CSX Corporation (NASDAQ:CSX) announced a new group of properties designated under its CSX Select Site program, with 21 sites across 10 states receiving gold, silver, or bronze ratings. The company said the program identifies rail-served locations suited for industrial development, noting that only about 6% of the more than 1,110 sites it serves qualify for the designation.

Earlier in March, Jefferies raised its price target on CSX Corporation (NASDAQ:CSX) to $50 from $42 and maintained a Buy rating, describing transportation infrastructure as “core HALO exposures,” or assets that are difficult to replicate and less vulnerable to disruption. The firm said these characteristics support long-term value in rail networks.

CSX Corporation (NASDAQ:CSX) provides rail-based freight transportation services across the United States and Canada.