10 Hottest Small Cap Stocks to Buy Now

​5. Avadel Pharmaceuticals plc (NASDAQ:AVDL)

Market Capitalization: $1.84 billion

6-Month Performance: 96.35%

Number of Hedge Fund Holders: 96.35%

​Avadel Pharmaceuticals plc (NASDAQ:AVDL) is one of the Hottest Small Cap Stocks to Buy Now. On November 5, Ami Fadia from Needham reiterated a Hold rating on Avadel Pharmaceuticals plc (NASDAQ:AVDL) without disclosing any price target.

​The rating follows the company’s Q3 2025 results released on November 4. During the quarter, the company grew its revenue by 54.86% year-over-year to $77.47 million, surpassing analysts’ estimates by $3.89 million. However, the EPS of $0 fell short of the expectations by $0.05. Management attributed revenue growth to robust sales of LUMRYZ and a 48% increase to 3,400 patients on LUMRYZ as of September 30, 2025.

​Although Avadel Pharmaceuticals plc (NASDAQ:AVDL) missed EPS estimates, its net income of $20,000 for the quarter was significant. The net income reflected a significant improvement versus the same quarter previous year, where the company reported a net loss of $2.6 million, translating to a negative EPS of $0.03. This was aided by a reversal of $9.5 million by Jazz in conjunction with the Settlement Agreement.

​Avadel Pharmaceuticals plc (NASDAQ:AVDL) is a biopharmaceutical company that develops extended-release drug formulations to improve patient treatment experiences. Their main product, LUMRYZ, is an FDA-approved once-at-bedtime extended-release sodium oxybate therapy for excessive daytime sleepiness in adults and children with narcolepsy.