10 Hottest Large-Cap Stocks of 2025

8. Oklo Inc. (NYSE:OKLO)

Market Capitalization as of December 29: $11.65 billion

Number of Hedge Fund Holders: 38

Year-to-Date Performance as of December 29: 250.31%

Oklo Inc. (NYSE:OKLO) is one of the hottest large-cap stocks of 2025. On December 8, Seaport Research analyst Jeff Campbell upgraded Oklo to Buy from Neutral with a $150 price target. This sentiment follows the company’s Q3 2025 earnings call, which the firm noted offered extensive detail on the multivariate progress of its business strategy. The new valuation is grounded in a 2032 EBITDA projection of $1.59 billion.

Previously, on December 5, Needham initiated coverage of Oklo Inc. (NYSE:OKLO) with a Buy rating and $135 price target. Needham cited the company’s advantaged regulatory standing and broad fuel strategy as key differentiators. With an industry-leading pipeline and over $1.2 billion in liquidity, the company is well-equipped to execute on multiple projects at once. A critical factor in this bullish outlook is the DOE authorization, which Needham believes greatly reduces the execution risks for its initial reactors.

Additionally, UBS analyst Jon Windham raised the firm’s price target on Oklo to $95 from $65 and keeps a Neutral rating on the shares on December 2. Positioned for a massive build-out of nuclear infrastructure, Oklo’s primary focus is its INL pilot project, targeting a July 2026 start-up. The firm noted that if Oklo Inc. (NYSE:OKLO) successfully commercializes its SMR technology early, it stands to gain a substantial first-mover advantage and rapidly expand its market presence.

Oklo Inc. (NYSE:OKLO) develops advanced fission power plants to provide clean, reliable, and affordable energy at scale to customers in the US. It also commercializes nuclear fuel recycling technology that converts nuclear waste into usable fuel for its reactors.