10 Best Strong Buy Stocks to Invest In Under $5

3. Taysha Gene Therapies, Inc. (NASDAQ:TSHA)

Number of Hedge Fund Holders: 32

Taysha Gene Therapies, Inc. (NASDAQ:TSHA) is one of the best strong buy stocks to invest in under $5. Needham maintained a bullish outlook on Taysha Gene Therapies, Inc. (NASDAQ:TSHA) on January 6, reiterating a Buy rating on the stock with a $10 price target. The rating update came the same day Taysha Gene Therapies, Inc. (NASDAQ:TSHA) announced the dosing of the first patient in the REVEAL pivotal trial evaluating TSHA-102 in Q4 2025, with enrollment advancing across multiple sites. It reported progress across the TSHA-102 pivotal program, an intrathecally delivered AAV9 gene therapy with disease-modifying potential, in clinical evaluation for the treatment of Rett syndrome.

The company also stated that it reached written alignment with the FDA regarding the inclusion of ≥3 months of safety data from the ASPIRE trial evaluating TSHA-102 in the planned BLA submission to support a broad label in patients aged ≥2 years with Rett syndrome. Dosing in the REVEAL pivotal trial and ASPIRE trial is anticipated to be completed in Q2 2026, with the longer-term safety and efficacy data update from Part A of REVEAL Phase 1/2 trials expected in H1 2026.

Taysha Gene Therapies, Inc. (NASDAQ:TSHA) is a clinical-stage biotechnology company that develops and commercializes adeno-associated virus (AAV) based gene therapies to treat monogenic diseases of the central nervous system.