10 Best Low Volatility Investments in December 2025

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7. Amgen Inc. (NASDAQ:AMGN)

Beta Value: 0.44

Dividend Yield: 2.76%

Number of Hedge Fund Holders: 62

Amgen Inc. (NASDAQ:AMGN) ranks among the Best Low Volatility Investments in December 2025. Goldman Sachs reaffirmed its $400 price target and Buy rating for Amgen Inc. (NASDAQ:AMGN) on November 25 ahead of two Phase 2 updates for the company’s obesity medication MariTide, which are anticipated by year’s end. Following previously disclosed induction results from Part 1, the firm anticipates that Amgen will provide maintenance data in obesity from Part 2 of its Phase 2 trial.

Goldman Sachs looked for long-term weight loss with reduced or occasional dosage and little gastrointestinal side effects in the obesity maintenance data. According to the firm, patients were only qualified for the maintenance phase if they experienced a weight loss of more than 15% in Part 1.

In the Phase 2 study, MariTide showed up to a 20% average weight loss in patients with obesity without Type 2 diabetes (T2D) and a roughly 17% average weight loss in those with T2D. MariTide weight loss was also associated with improvements in pre-specified cardiometabolic parameters, such as waist circumference and blood pressure.

Amgen Inc. (NASDAQ:AMGN) discovers, develops, manufactures, and delivers human therapeutics worldwide. The company serves healthcare providers, including physicians or their clinics, dialysis centers, hospitals, and pharmacies.

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