In this article, we are going to discuss the 10 best Fortune 500 stocks to buy according to Wall Street analysts.
The S&P 500 index, which tracks a majority of the American Fortune 500 companies, is currently hovering around its all-time high. As of the writing of this piece, the index has posted gains of 5% since the beginning of 2026, despite being weighed down by the conflict in the Middle East.
The index has received strong support from the better-than-expected results posted by Big Tech in the ongoing earnings season, with S&P 500 profits now expected to grow 27.8% in the first quarter, the strongest since the fourth quarter of 2021. According to UBS, companies representing around 70% of the index market cap have already reported their Q1 earnings, with approximately 80% of them beating sales and EPS estimates. Moreover, the US manufacturing sector also continued to expand in April, and consumer spending remained resilient.
With overall guidance pointing to solid earnings also in the second quarter, UBS maintains a solid outlook for US equities and sees attractive investment opportunities across financials, health care, industrials, utilities, and consumer discretionary sectors.
With that said, here are the Best Large Cap Stocks to Invest in According to Analysts.
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Our Methodology
To collect data for this article, we scanned the top companies among the Fortune Global Rankings and shortlisted stocks with the highest upside potential according to Wall Street analysts, as of May 3, 2026. We then limited our final selection to companies that have recently reported noteworthy developments likely to impact investor sentiment. The following are the Best Large Cap Stocks to Buy According to Analysts.
Why are we interested in the stocks that hedge funds pile into? The reason is simple: our research has shown that we can outperform the market by imitating the top stock picks of the best hedge funds. Our quarterly newsletter’s strategy selects 14 small-cap and large-cap stocks every quarter and has returned 498.7% since May 2014, beating its benchmark by 303 percentage points (see more details here).
10. Amazon.com, Inc. (NASDAQ:AMZN)
Upside Potential as of May 3: 17.42%
Amazon.com, Inc. (NASDAQ:AMZN) provides a broad selection, value, and convenience across a range of customer experiences, including online shopping, cloud computing, streaming entertainment, consumer electronic devices, advertising, healthcare, AI services, and more.
On April 30, Goldman Sachs upped its price target on Amazon.com, Inc. (NASDAQ:AMZN) from $275 to $325, while keeping a ‘Buy’ rating on the shares. The target boost represents an upside potential of over 19% from the current share price.
Amazon delivered a strong Q1 2026 report on April 29, exceeding estimates in both earnings and revenue. The company grew its revenue by over 16% YoY to $181.5 billion, above the top end of guidance, driven by strength in Online Stores and AWS, which delivered the fastest growth rate in 15 quarters. Moreover, AWS boasted a backlog of $364 billion in the first quarter, supporting sustained growth.
Amazon.com, Inc. (NASDAQ:AMZN) is expecting its Q2 net sales to be between $194 billion and $199 billion, with operating income forecasted in the range of $20 billion and $24 billion.
9. The Cigna Group (NYSE:CI)
Upside Potential as of May 3: 20.18%
The Cigna Group (NYSE:CI) is a global health company that provides insurance and related products and services. It operates through two segments: Evernorth Health Services and Cigna Healthcare.
On May 1, Barclays increased its price target on The Cigna Group (NYSE:CI) from $303 to $310, while maintaining an ‘Overweight’ rating on the shares. The raised target, which represents an upside of almost 10% from the current levels, comes following the company’s Q1 report.
The Cigna Group (NYSE:CI) posted strong results for its first quarter on April 30, exceeding estimates in both profits and revenue. The company grew its adjusted EPS by around 16% YoY to $7.79, while its revenue of $68.5 billion was also up by 4.7% compared to last year. Notably, Cigna also revealed that it would exit subsidized plans offered under the Affordable Care Act, also known as Obamacare, at the end of this year.
The Cigna Group (NYSE:CI) also raised its full-year 2026 consolidated adjusted earnings per share outlook to at least $30.35, up from the prior guidance of $30.25 and slightly better than the consensus of $30.33.
