| No. | Hedge Fund | Shares | Value | Activity | % Port |
|---|---|---|---|---|---|
| 1. | Pura Vida Investments Efrem Kamen | 0 | $0 | 0% | |
| 2. | Blue Jay Capital Management Paul Sinclair | 0 | $0 | 0% | |
| 3. | VenBio Select Advisor Kurt Von Emster | 0 | $0 | 0% | |
| 4. | Cormorant Asset Management Bihua Chen | 0 | $0 | 0% | |
| 5. | Rock Springs Capital Management Kris Jenner, Gordon Bussard, Graham Mcphail | 0 | $0 | 0% |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $51.55 | 100 | Director | 300 | 2014-03-17 | Filing | |
| $50.23 | 200 | Director | 200 | 2014-03-14 | Filing | |
| $14.00 | 142,857 | Large Shareholder | 2,081,210 | 2013-05-14 | Filing | |
| $14.00 | 142,857 | Large Shareholder | 2,081,210 | 2013-05-14 | Filing | |
| $14.00 | 284,485 | Large Shareholder | 2,101,376 | 2013-05-14 | Filing |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $182.89 | 50,400 | Director | 665,561 | 2015-06-16 | Filing | |
| $175.54 | 88,400 | Director | 715,961 | 2015-06-15 | Filing | |
| $180.33 | 81,200 | Director | 804,361 | 2015-06-12 | Filing | |
| $154.46 | 12,500 | Officer | 0 | 2015-05-01 | Filing | |
| $130.15 | 7,200 | Director | 885,561 | 2015-02-27 | Filing |
