| No. | Hedge Fund | Shares | Value (x$1000) | Activity | % Port |
|---|---|---|---|---|---|
| 1.) | 85,000,000 | $139,334 | +55% |
15.73% | |
| 2.) | Partner Fund Management Christopher Medlockï¾ James |
3,860,907 | $283,584 | +36% |
11.91% |
| 3.) | 55,500,000 | $90,951 | +825% |
8.17% | |
| 4.) | Healthcor Management Lp Arthur B Cohen And Joseph Healey |
1,225,000 | $89,976 | -2% |
4.92% |
| 5.) | 24,600,000 | $41,492 | -14% |
4.86% | |
| 6.) | Visium Asset Management Jacob Gottlieb |
1,753,167 | $128,770 | +28% |
4.47% |
| 7.) | Sectoral Asset Management J�R�Me Pfund And Michael Sj�Str�M |
1,680,331 | $123,420 | -7% |
4.31% |
| 8.) | Blue Ridge Capital John Griffin |
4,000,000 | $293,800 | +12% |
4.08% |
| 9.) | Bridger Management Roberto Mignone |
750,000 | $55,088 | +3% |
3.92% |
| 10.) | Sirios Capital Management John Brennan |
231,220 | $16,983 | +3% |
2.97% |
| 11.) | Orbimed Advisors Samuel Isaly |
2,424,100 | $89,025 | -19% |
2.74% |
| 12.) | 18,223,000 | $35,150 |  |
2.33% | |
| 13.) | Traxis Partners Barton Biggs |
33,083 | $2,430 | |
2.33% |
| 14.) | 34,500,000 | $56,575 | +73% |
2.3% | |
| 15.) | Alydar Capital John Murphy |
350,000 | $25,708 | |
2% |
| 16.) | Perceptive Advisors Joseph Edelman |
143,100 | $10,511 | -48% |
1.85% |
| 17.) | Columbus Circle Investors Donald Chiboucis |
2,783,936 | $204,480 | +22% |
1.64% |
| 18.) | Platinum Asset Management Kerr Neilson |
946,651 | $69,531 | -37% |
1.55% |
| 19.) | Wexford Capital Charles Davidson |
257,400 | $18,906 | |
1.39% |
| 20.) | 40,000,000 | $65,550 | +700% |
1.29% |
| Insider | Price | Amount | Relationship | Remaning Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $43.05 | 10,000 | Director | 69,458 | 2013-02-28 | Filing | |
| $44.00 | 10,000 | Director | 26,097 | 2012-02-22 | Filing | |
| $48.28 | 2,500 | Director | 2,742 | 2009-07-24 | Filing |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $50.17 | 282,242 | Director | 4,057,121 | 2013-05-01 | Filing | |
| $50.20 | 30,000 | Officer | 63,938 | 2013-05-01 | Filing | |
| $50.20 | 968 | Officer | 27,130 | 2013-04-11 | Filing | |
| $48.42 | 10,000 | Officer | 28,098 | 2013-04-01 | Filing | |
| $48.03 | 3,000 | Officer | 28,098 | 2013-04-01 | Filing |
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