| No. | Hedge Fund | Shares | Value (x$1000) | Activity | % Port |
|---|---|---|---|---|---|
| 1.) | Orbimed Advisors Samuel Isaly |
4,111,000 | $169,332 | +100% |
3.93% |
| 2.) | Kahn Brothers Irving Kahn |
414,427 | $17,070 |  |
2.51% |
| 3.) | Deerfield Management James E. Flynn |
650,000 | $26,774 | |
1.6% |
| 4.) | Renaissance Technologies Jim Simons |
14,115,900 | $581,434 | |
1.4% |
| 5.) | Adage Capital Management Phill Gross And Robert Atchinson |
5,516,158 | $227,211 | |
0.75% |
| 6.) | Bailard Inc Thomas Bailard |
84,163 | $3,467 | |
0.65% |
| 7.) | Vertex One Asset Management John Thiessen |
100,242 | $4,129 | |
0.56% |
| 8.) | Winton Capital Management David Harding |
632,352 | $26,047 | |
0.47% |
| 9.) | P.a.w. Capital Partners Peter A. Wright |
12,000 | $494 | |
0.36% |
| 10.) | Advanced Investment Partners Douglas W. Case |
42,157 | $1,736 |  |
0.34% |
| 11.) | 350,000 | $14,417 | |
0.33% | |
| 12.) | Polar Capital Brian Ashford-Russell And Tim Woolley |
160,000 | $6,587 | |
0.26% |
| 13.) | Gamco Investors Mario Gabelli |
951,995 | $39,213 | |
0.25% |
| 14.) | 1,253,700 | $51,640 | |
0.19% | |
| 15.) | Two Sigma Advisors John Overdeck And David Siegel |
274,443 | $11,305 | +800% |
0.18% |
| 16.) | Citadel Investment Group Ken Griffin |
1,412,324 | $58,174 | +200% |
0.08% |
| 17.) | 497,600 | $20,496 | |
0.07% | |
| 18.) | Bridgewater Associates Ray Dalio |
181,140 | $7,461 | +200% |
0.06% |
| 19.) | Millennium Management Israel Englander |
367,912 | $15,154 | |
0.06% |
| 20.) | Mckinley Capital Management Robert B. Gillam |
27,660 | $1,139 | |
0.05% |
| Insider | Price | Amount | Relationship | Remaning Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $25.73 | 900 | Director | 369,737 | 2011-02-17 | Filing | |
| $19.18 | 15,000 | Officer | 178,376 | 2009-04-30 | Filing | |
| $19.25 | 25,000 | Officer | 25,000 | 2009-04-30 | Filing |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $47.24 | 25,000 | Officer | 29,584 | 2013-06-10 | Filing | |
| $47.74 | 100,000 | Director | 478,562 | 2013-06-04 | Filing | |
| $47.38 | 58,898 | Officer | 24,687 | 2013-06-04 | Filing | |
| $46.33 | 25,997 | Officer | 42,274 | 2013-06-05 | Filing | |
| $46.53 | 26,275 | Officer | 68,342 | 2013-06-06 | Filing |
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