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Under-the-Radar Hedge Fund Focusing on Pharmacyclics, Inc. (PCYC), Novadaq Technologies Inc. (NVDQ)

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Hedge funds are typically thought of as being billion dollar funds managed by Harvard MBAs and alums of some of Wall Street’s more prestigious analyst programs (i.e. Goldman Sachs, JP Morgan).  Interestingly, Dafna Capital Management is neither large (only $63 million) and is managed by Dr. Nathan Fischel MD and his wife, a biomedical engineer.  So why are we even talking about Dafna?  Because according to the most recent data compiled by Insider Monkey, Dafna’s equity portfolio was one of the best 10 of those we track last year.

More importantly, it’s always beneficial to track the smart money’s sentiment, and our market-beating strategies explain this “truth” quite nicely (learn the details here).

Pharmacyclics, Inc. (NASDAQ:PCYC)

First in this hedgie’s top five is Pharmacyclics, Inc. (NASDAQ:PCYC).  The stock rallied to a 13-year high of $77.03 after the FDA gave the drug-maker a “breakthrough” designation, a distinction that leads to faster approvals for new drugs to hit the market.  The news is expected to hasten the FDA’s approval of Pharmacyclics, Inc. (NASDAQ:PCYC)’s Ibrutinib, a cancer-drug that that blocks the enzyme that causes certain cancers to spread such as non-Hodgkin lymphoma. As a result of the recent rally, Pharmacyclics, Inc. (NASDAQ:PCYC) is priced very expensive to the rest of this sector, but all of its other financials are extremely bullish—revenue, net income, EPS, for example—and will continue to improve once Ibrutinib comes to the market.

Sitting at No. 2 is YM BioSciences Inc. (USA) (NYSEAMEX:YMI). YM Biosciences was purchased by Gilead Sciences for $2.95 a share in February, and at the time Dafna first added YM to its portfolio in Q2 2011, the stock was trading below the $2 mark; not a bad gain for a two-year investment. Michael Hintze and John Thiessen were a couple other fund managers invested in this company heading into 2013; see the complete list here.

Third up is Novadaq Technologies Inc. (NASDAQ:NVDQ).  Novadaq rallied earlier this year following a very strong earnings report. Sales devoted to costs improved from 45% to 39% and Q4 gross profit improved 56% from the same period last year. However, after hitting a high of $10.80, the stock’s momentum seems to be slowing down, and it has stalled above the $10.50 level.  Technicals are neutral-to-bearish, and there isn’t any bullish news for Novadaq Technologies Inc. (NASDAQ:NVDQ) in the pipeline.  Dafna’s position in the stock was reduced by 8% in the latest quarter, and we’d watch this stock very carefully moving forward.

Fourth in Dafna’s top five is Insulet Corporation (NASDAQ:PODD), a medical devices manufacturer which specializes in insulin pumps, blood-glucose testing supplies and other products for the treatment of diabetes. Like Novadaq, a positive earnings report for the fourth quarter drove the stock to a solid level—above $24.00 in this case.  Although there was some light profit taking, the stock is maintaining most of its gains, but…

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