Bellicum Pharmaceuticals Inc (BLCM): Baker Bros. Discloses 16% Passive Stake

As a new filing with the Securities and Exchange Commission showed, Bellicum Pharmaceuticals Inc (NASDAQ:BLCM) has been added to the equity portfolio of Julian and Felix Bakers‘ healthcare-focused hedge fund Baker Bros. Advisors. The filing revealed that the fund holds around 4.28 million shares of the company, which represent approximately 16.3% of its outstanding common stock, while the stake is passive by nature. Bellicum Pharmaceuticals went public in December and as the S-1 filing of the company shows, Baker Bros. has been among the stockholders of the company before the IPO.

Felix Baker - Baker Bros.

However, Baker Bros. has increased its stake right after the company went public. Prior to the IPO, its affiliate, Baker Biotech Capital held some 3.21 million shares, which represented 19.4% before the offering and would’ve been reduced to 12.3%. Meanwhile, since the company started trading on NASDAQ on December 18, its stock has already gained over 30%. Bellicum Pharmaceuticals is an $800 million clinical-stage biopharmaceutical company, which is engaged in discovering and developing cellular immunotherapies for different forms of cancers, including solid tumors and orphan inherited blood disorders. Today the company announced that it has completed the dosing with its genetically engineered donor T cells (BPX-501) of the first cohort of patients. The BPX-501 is evaluated as adjung T cell therapy in patients with hematologic cancers.

Another shareholder of Bellicum Pharmaceuticals Inc (NASDAQ:BLCM) is Peter Kolchinsky‘s RA Capital Management. As the same S-1 filing, showed, Kolchinsky’s RA Capital Healthcare Fund held some 801,400 shares as the company went public. However, after the IPO, RA Capital’s stake in the company declined to 3.2% from 5.4% and since institutional investors are obliged to disclose only stakes that are over 5% of stock, RA has not issued any information regarding its holding in Bellicum. RA Capital is another healthcare-focused hedge fund that invests in companies with promising drugs or technologies.

Moreover, as the company went public, several analysts initiated coverage giving optimistic prospects about the company’s future. Also on Tuesday, right after Bellicum Pharmaceuticals Inc (NASDAQ:BLCM) announced that it has completed dosing with its BPX-501, Citigroup initiated coverage setting a ‘Buy’ rating with a price target of $36.00. Moreover, Piper Jaffray has an ‘Overweight’ rating for the stock with a price target of $45.00, while Jefferies Group has initiated coverage with ‘Buy’ rating and set a price target of $35.00.

In this way, it looks like Baker Bros. has made a profitable bet by investing in Bellicum Pharmaceuticals Inc (NASDAQ:BLCM). It is not surprising, since the fund that manages a $7 billion equity portfolio is mainly focused on biotech stocks, in which it has developed a deep expertise.

Among other stocks that Baker Bros. has been bullish on in the last months is Seattle Genetics, Inc. (NASDAQ:SGEN), of which it owns around 28.11 million shares, which represent 22.7% of the company. The fund has been raising its stake in the company for the last several years and has been holding shares since 2004, witnessing the stock gaining more than 400%. Pharmacyclics, Inc. (NASDAQ:PCYC) is the largest position in Baker Bros’ equity portfolfio as of the end of September, and the stock also has had an impressive run over the years, growing by a tenfold over the last ten years.

Disclosure: none