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RBC Capital Initiates Pfizer (PFE) with $25 Target, Warns of Structural Revenue Headwinds

Pfizer Inc. (NYSE:PFE) is included among the 14 Best Affordable Dividend Stocks to Buy According to Analysts.

Photo by Dan Dennis on Unsplash

On February 25, RBC Capital initiated coverage of Pfizer Inc. (NYSE:PFE) with an Underperform rating and a $25 price target. The firm said its outlook reflects an “insurmountable” $15B-$20B revenue decline expected through 2030, with limited visibility into new products that could help offset the loss. The analyst noted that Pfizer’s roughly 6% dividend yield offers some support and stands above the peer average. Even so, that alone may not be enough to counter deeper structural challenges. The firm also sees a lack of meaningful catalysts heading into 2026, according to the research note.

Pfizer also signed a licensing agreement with China-based Sciwind Biosciences for its type 2 diabetes drug, ecnoglutide. Under the agreement, Sciwind could receive up to $495 million in milestone payments, along with an upfront fee that was not disclosed. Pfizer will gain the rights to commercialize the drug in mainland China.

Sciwind said the partnership supports Pfizer’s broader expansion in China’s metabolic disease market. Ecnoglutide belongs to the GLP-1 receptor agonist class, which helps regulate blood sugar and control appetite. This category has drawn strong interest across the industry, with companies like Novo Nordisk, Eli Lilly, Innovent Biologics, and Guangzhou Innogen investing heavily in similar treatments.

The drug received approval in China in January. Sciwind has also submitted an application for a version aimed at weight management. Pfizer recently licensed another experimental GLP-1 treatment from a different Chinese drugmaker, signaling continued focus on this fast-growing area.

Pfizer did not disclose the upfront payment amount, launch timing, or expected pricing. Unlike some competing GLP-1 drugs, including Novo Nordisk’s Ozempic and Eli Lilly’s Mounjaro, ecnoglutide will not be covered under China’s national health insurance program for diabetes treatment.

Pfizer Inc. (NYSE:PFE) operates as a global biopharmaceutical company focused on discovering, developing, manufacturing, and marketing medicines worldwide.

While we acknowledge the potential of PFE to grow, our conviction lies in the belief that some AI stocks hold greater promise for delivering higher returns and have limited downside risk. If you are looking for an AI stock that is more promising than PFE and that has 100x upside potential, check out our report about this cheapest AI stock.

READ NEXT: 13 Best Strong Buy Dividend Stocks to Invest In and Goldman Sachs Dividend Stocks: Top 14 Stock Picks

Disclosure: None.  Follow

The $250 Trillion AI Hype is Real. A few years from now, you’ll probably wish you’d bought this stock.

Dr. Inan Dogan

Dr. Ian Dogan

Co-Founder and Research Director at Insider Monkey

When Jeff Bezos said that one breakthrough technology would shape Amazon’s destiny, even Wall Street’s biggest analysts were caught off guard.

Fast forward a year and Amazon’s new CEO Andy Jassy described generative AI as a “once-in-a-lifetime” technology that is already being used across Amazon to reinvent customer experiences.

At the 8th Future Investment Initiative conference, Elon Musk predicted that by 2040 there would be at least 10 billion humanoid robots, with each priced between $20,000 and $25,000.

Do the math. According to Musk, this technology could be worth $250 trillion by 2040.

Put another way, that’s roughly equal to:

  • 175 Teslas
  • 107 Amazons
  • 140 Metas
  • 84 Googles
  • 65 Microsofts
  • And 55 Nvidias

And here’s the wild part — this $250 trillion wave isn’t tied to one company, but to an entire ecosystem of AI innovators set to reshape the global economy.

It’s a leap so massive, it could reshape how businesses, governments, and consumers operate worldwide.

Even if that $250 trillion figure sounds ambitious, major firms like PwC and McKinsey still see AI unlocking multi-trillion-dollar potential.

How could anything be worth that much?

The answer lies in a breakthrough so powerful it’s redefining how humanity works, learns, and creates.

And this breakthrough has already set off a frenzy among hedge funds and Wall Street’s top investors.

What most investors don’t realize is that one under-owned company holds the key to this $250 trillion revolution.

In fact, Verge argues this company’s supercheap AI technology should concern rivals.

Before I reveal the details, let’s talk about how some of the richest people on the planet are positioning themselves.

  • Bill Gates sees artificial intelligence as the “biggest technological advance in my lifetime,” more transformative than the internet or personal computer, capable of improving healthcare, education, and addressing climate change.
  • Larry Ellison — through Oracle, is spending billions on Nvidia chips and partnering with Cohere to embed generative AI across Oracle’s cloud and apps.
  • Warren Buffett — not known for tech hype — says this breakthrough could have a ‘hugely beneficial social impact.

When billionaires from Silicon Valley to Wall Street line up behind the same idea — you know it’s worth paying attention to.

Even as we admire what Tesla, Nvidia, Alphabet, and Microsoft have built, we believe an even greater opportunity lies elsewhere…

But the real story isn’t Nvidia — it’s a much smaller company quietly improving the critical technology that makes this entire revolution possible.

And judging by what I’m hearing from both Silicon Valley insiders and Wall Street veterans…

This prediction might not be bold at all:

A few years from now, you’ll wish you’d owned this stock.

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Dr. Inan Dogan

Dr. Ian Dogan

Co-Founder and Research Director at Insider Monkey

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