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Jazz Pharmaceuticals plc (JAZZ) Advances Rare Cancer Portfolio with First CNS Glioma Therapy Approval

In this article, we will be taking a look at the 10 Best Pharma Stocks to Buy According to Billionaires. Jazz Pharmaceuticals plc is one of them.

Jazz Pharmaceuticals plc (NASDAQ:JAZZ) continues to advance its mission to transform patient lives through innovative therapies for conditions with limited treatment options. The company’s marketed products lead in sleep medicine (Xywav, Xyrem), epilepsy (Epidiolex), and oncology (Zepzelca), while strategic acquisitions, including GW Pharmaceuticals and Chimerix, have strengthened its pipeline with promising investigational drugs. The stock stands tenth on our list among the best pharmaceutical stocks. 

On August 6, 2025, Jazz Pharmaceuticals plc (NASDAQ:JAZZ) received FDA accelerated approval for Modeyso (dordaviprone), a DRD2 antagonist for patients with relapsed H3 K27M-mutated diffuse midline glioma. Modeyso is the first approved therapy for this ultra-rare CNS cancer, demonstrating a 22% overall response rate in a pooled analysis of 50 patients across five trials. While the label carries warnings for hypersensitivity and QTc prolongation, these risks are considered acceptable given the aggressive nature of the disease. Continued approval will depend on results from the confirmatory Phase III Action trial, with interim data expected by year-end 2025.

The approval underscores JAZZ’s growing focus on rare oncology indications. The business is also advancing Zepzelca for small-cell lung cancer, planning a supplemental New Drug Application for frontline use based on positive Phase III results, and zanidatamab, a HER2-targeted bispecific antibody in pivotal trials for gastroesophageal adenocarcinoma, with results expected in Q2 2025.

Looking ahead, Jazz Pharmaceuticals plc (NASDAQ:JAZZ)is poised for near-term growth with the commercial launch of Modeyso, ongoing pivotal trial readouts, and regulatory submissions for expanded indications.

While we acknowledge the risk and potential of JAZZ as an investment, our conviction lies in the belief that some AI stocks hold greater promise for delivering higher returns and doing so within a shorter time frame. If you are looking for an AI stock that is more promising than JAZZ and that has 10,000% upside potential, check out our report about this cheapest AI stock.

READ NEXT: 30 Stocks That Should Double in 3 Years and 11 Hidden AI Stocks to Buy NOW 

Disclosure: None.

The $250 Trillion AI Hype is Real. A few years from now, you’ll probably wish you’d bought this stock.

When Jeff Bezos said that one breakthrough technology would shape Amazon’s destiny, even Wall Street’s biggest analysts were caught off guard.

Fast forward a year and Amazon’s new CEO Andy Jassy described generative AI as a “once-in-a-lifetime” technology that is already being used across Amazon to reinvent customer experiences.

At the 8th Future Investment Initiative conference, Elon Musk predicted that by 2040 there would be at least 10 billion humanoid robots, with each priced between $20,000 and $25,000.

Do the math. According to Musk, this technology could be worth $250 trillion by 2040.

Put another way, that’s roughly equal to:

  • 175 Teslas
  • 107 Amazons
  • 140 Metas
  • 84 Googles
  • 65 Microsofts
  • And 55 Nvidias

And here’s the wild part — this $250 trillion wave isn’t tied to one company, but to an entire ecosystem of AI innovators set to reshape the global economy.

It’s a leap so massive, it could reshape how businesses, governments, and consumers operate worldwide.

Even if that $250 trillion figure sounds ambitious, major firms like PwC and McKinsey still see AI unlocking multi-trillion-dollar potential.

How could anything be worth that much?

The answer lies in a breakthrough so powerful it’s redefining how humanity works, learns, and creates.

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What most investors don’t realize is that one under-owned company holds the key to this $250 trillion revolution.

In fact, Verge argues this company’s supercheap AI technology should concern rivals.

Before I reveal the details, let’s talk about how some of the richest people on the planet are positioning themselves.

  • Bill Gates sees artificial intelligence as the “biggest technological advance in my lifetime,” more transformative than the internet or personal computer, capable of improving healthcare, education, and addressing climate change.
  • Larry Ellison — through Oracle, is spending billions on Nvidia chips and partnering with Cohere to embed generative AI across Oracle’s cloud and apps.
  • Warren Buffett — not known for tech hype — says this breakthrough could have a ‘hugely beneficial social impact.

When billionaires from Silicon Valley to Wall Street line up behind the same idea — you know it’s worth paying attention to.

Even as we admire what Tesla, Nvidia, Alphabet, and Microsoft have built, we believe an even greater opportunity lies elsewhere…

But the real story isn’t Nvidia — it’s a much smaller company quietly improving the critical technology that makes this entire revolution possible.

And judging by what I’m hearing from both Silicon Valley insiders and Wall Street veterans…

This prediction might not be bold at all:

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