We recently shared a list of 10 Best Short Squeeze Stocks To Buy According to Analysts. In this article, we will see how Taysha Gene Therapies, Inc. (NASDAQ:TSHA) compares to the other top short squeeze stocks that have received a Buy rating from analysts.

Stock market trading has an ever-changing environment. Short squeeze is among the few phenomena capable of capturing and holding the attention of such markets. The phenomenon involves a heavily shorted stock suddenly experiencing a rapid price increase, urging short sellers to buy shares to cover their positions, thereby accelerating the upward momentum. Astute investors make significant gains out of the scenario upon identifying these opportunities in their early stages. After Donald Trump’s ascension to the U.S. Presidency, recent market activities have demonstrated the significance of short squeezes.

READ ALSO: 10 Best Short-Term Stocks To Buy Right Now

Tariff rates were the first aspect to take a hit and directly impact the stock market after President Trump’s arrival in the White House. The U.S. announced a 25% tariff on imports from Mexico and Canada, effective March 4, 2025. The announcement came alongside increased tariffs on Chinese goods from 10% to 20%. These new tariff rates sent ripples through the financial markets, affecting the stocks in the U.S. and beyond, as countries like Canada started countering the move by threatening to increase tariffs on U.S. products as well.

By March 6, 2025, the U.S. President signed orders and brought many goods to the list of exemptions from his new tariffs on Canada and Mexico. For instance, CNN reported a temporary halt on the new 25% tariff rates on imports for carmakers from Canada and Mexico. However, the decision did not alleviate the substantial adverse effect the U.S. stock market felt. CNBC noted that individual investors pulled $1.2 billion from the U.S. equity market, the highest ever in the decade.

However, tariffs do not only affect the volatility of the U.S. market. Various incidents contribute to the shifts in the broader market, setting the stage for potential short squeezes. For instance, the advent of new AI models from China initially caused a wave in the technological industry, leading many of the giant tech companies to witness a never-before-seen decline in their return. These foreign AI models were comparatively more flexible yet cheaper than their U.S. counterparts, thus resulting in many investors pulling their investment from tech companies.

The hedge funds have been reducing their holdings in Chinese equities for the fourth consecutive week; however, the enthusiasm for Chinese tech stocks, initially sparked by the new AI startups, began to wane. The trend reflects a cautious approach, possibly opening avenues for short-squeeze opportunities in other sectors.

Furthermore, Asia-focused hedge funds have performed better than their U.S. counterparts during recent market sell-offs. Owing to the recent market volatility in the U.S., global investors sought refuge in the Chinese stocks, eventually contributing to this outperformance. These events increase the potential for short-squeeze scenarios in different markets, including the U.S.

These developments have led to an upward trend in the attention of analysts on stocks with high short interest and substantial upside potential. Hence, investors will find it beneficial to their investment portfolio to delve into the top 10 short-squeeze stocks to consider, as recommended by leading analysts.​

Our Methodology

We compiled our list using a few key financial metrics. Primarily, we took stocks with Short Float of over 15%. This is a critical factor for potential short squeezes, representing significant short interest. We also filtered our list based on Relative volume. Our list comprises stocks with a Relative Volume of over 1.5, indicating higher-than-usual trading activity.

Additionally, we included only those with Positive EPS to signify profitability. We refined our selection further by considering only the stocks with a Buy or better recommendation from analysts, as this ensured they had favorable market sentiment. Lastly, we included only stocks with an average trading volume of at least 100K, providing sufficient liquidity. The final list was ranked based on the analysts’ upside potential, which was used to deliver the highest expected price appreciation in our article. We also found it helpful to mention the number of hedge funds from Insider Monkey’s Q4 2024 database, following each stock in our list, to allow the investors to understand their level of institutional interest.

Why are we interested in the stocks that hedge funds pile into? The reason is simple: our research has shown that we can outperform the market by imitating the top stock picks of the best hedge funds. Our quarterly newsletter’s strategy selects 14 small-cap and large-cap stocks every quarter and has returned 373.4% since May 2014, beating its benchmark by 218 percentage points (see more details here).

Taysha Gene Therapies, Inc. (NASDAQ:TSHA)

Short % of Float: 16.43%

Number of Hedge Fund Holders: 20

Analysts Upside Potential: 306.98%

Based in Dallas, Texas, a clinical-stage biotechnology company, Taysha Gene Therapies, Inc. (NASDAQ:TSHA) focuses on gene therapies for rare neurological disorders. Unlike most competitors, the company leverages a targeted approach involving AAV-based gene therapy to address central nervous system diseases. Based on its mission statement, the company is developing transformative gene therapies to eradicate monogenic diseases of the central nervous system (CNS).

Taysha Gene Therapies, Inc. (NASDAQ:TSHA) has a short interest of 16.43%, positioning it as a candidate for a short squeeze. In the recent quarter, the company has seen increased expenses, including R&D and administrative costs. The expenses are rewarding since the company has announced positive clinical data from its TSHA-102 program. The program showed functional gains in patients with Rett syndrome. Additionally, the company has completed dosing in Part A of its REVEAL trials and is moving toward the pivotal Part B trials. These positive results place the company among the best short-squeeze stocks.

With 20 hedge funds holding stakes in Taysha Gene Therapies, Inc. (NASDAQ:TSHA) from the Insider Monkey database at the end of Q4 2024, the stock has received a Buy rating from analysts, thereby gaining a strong institutional watch. Analysts predict a massive 306.98% upside, setting a price target of $7. At the current price of $1.72, TSHA offers an attractive opportunity for substantial gains driven by short-covering activity.

Overall, TSHA ranks 2nd on our list of 10 best short squeeze stocks to buy, according to analysts. While we acknowledge the potential for TSHA as an investment, our conviction lies in the belief that some AI stocks hold more significant promise for delivering higher returns and doing so within a shorter time frame. If you are looking for an AI stock that is more promising than TSHA but that trades at less than 5 times its earnings check out our report about the cheapest AI stock.

READ NEXT: 20 Best AI Stocks To Buy Now and 30 Best Stocks To Invest In According to Billionaires.

Disclosure: None. This article is originally published at Insider Monkey.