We recently compiled a list of the Jeff Bezos Investments in 2025: 12 Companies Bezos Is Investing In. In this article, we are going to take a look at where Sana Biotechnology, Inc. (NASDAQ:SANA) stands against the other companies Bezos is investing in.
Since leaving his position as CEO of Amazon in 2021, Jeff Bezos has been quite active. He has been investing in real estate and companies, staying involved with Amazon and Blue Origin, and becoming close to President-elect Trump. “I’ve actually never worked harder,” he told the New York Times last December.
Jeff Bezos has directly invested in at least 108 startups across all industries since 1998, when he was reported to have invested $250,000 into Google. Although he does not publish his returns nor do the firms in which he invests, he has made early bets on several companies that have gone on to launch some of the most high-profile tech IPOs in the recent decade.
He certainly has enough cash to play with. According to Forbes, Bezos has sold around $32 billion in his main company shares since its initial public offering, including nearly $14 billion last year. He is now the third richest person in the world, with a net worth of $237 billion.
Although Bezos has spent a lot of time and money on yachts, aircraft, and real estate since transitioning from CEO to chairman of Amazon in 2021, he remains actively involved in his venture portfolio, advising portfolio firms and assisting with investment selections. However, Bezos isn’t as engaged as, say, a typical large venture capital firm: he was only the lead investor in one funding round last year (for Swiss-Mile), which means he likely didn’t acquire significant stakes in the majority of the companies, and he isn’t known to hold a board seat at any of the startups he has backed.
Two of the companies Forbes contacted said that a Bezos spokesman asked them not to discuss with the media about the Bezos investment, but those who did speak favorably about it. Swiss-Mile’s Bjelonic, Chief Executive Officer & Co-Founder, made the following comment:
“What I was most surprised with was actually how well he understood the technology behind the Al training. He would ask questions about reinforcement learning, imitation learning, how it works, going all the way to the details of the physics elements that are needed on our side.”
Regardless of how invested Bezos is in any given company, publicizing his name as an investor provides marketing exposure.
The autonomous robot business is still in its early stages of commercialization. Bjelonic compared the business to a “blue ocean,” predicting that in ten years, hundreds of robotics startups will fail while only a few will flourish. It will take years to determine whether those bets pay off.
However, the chances may be in Bezos’ favor, in part because he can combine his economic expertise with the fact that he will almost certainly be able to invest in any firm he chooses.
According to Columbia Business School professor Michael Ewens, the “best” and “hottest” startups reach out to people like Bezos first.
“In general, he’s a very good investor, because he’s getting calls. He’s first in line.”
A scientist working with a microscope in a laboratory, focusing on a cell of a medical experiment.
Methodology
We examined the investments of Bezos Expeditions, Jeff Bezos’ family office, to identify key companies he’s invested in. All selected firms are publicly traded except the last one, and the stocks are ranked in ascending order using Insider Monkey’s database of over 1,000 hedge funds in Q4 2024 to gauge hedge fund sentiment for stocks. The portfolio also includes one of his most recent private company investments, which is ranked last on our list.
Why are we interested in the stocks that hedge funds pile into? The reason is simple: our research has shown that we can outperform the market by imitating the top stock picks of the best hedge funds. Our quarterly newsletter’s strategy selects 14 small-cap and large-cap stocks every quarter and has returned 373.4% since May 2014, beating its benchmark by 218 percentage points (see more details here).
Sana Biotechnology, Inc. (NASDAQ:SANA)
Number of Hedge Fund Investors: 24
Jeff Bezos is investing in Sana Biotechnology, Inc. (NASDAQ:SANA), a high-tech healthcare company that develops cell engineering platforms for a range of therapeutic uses. It is transforming cell treatment with its immune evasion technology, which allows transplanted cells to thrive without the use of immunosuppressive drugs. A recent successful human trial of immune-evasive pancreatic islets reveals its potential for treating type 1 diabetes and other conditions. The company’s invention, which has applications for liver tissue, blood vessels, and T cells, has the possibility to alter the cell therapy landscape.
Immunosuppressive drugs, which are now the most common option for such treatments, not only have minimal long-term effects in preventing cell rejection but also pose serious hazards by impairing the patient’s immune system. Sana Biotechnology, Inc. (NASDAQ:SANA)’s method eliminates this dependency, allowing patients to have a normal immune system while their transplanted cells thrive. This has the potential to transform the treatment of chronic diseases ranging from diabetes to cancer, resulting in a multibillion-dollar market for cell-based medicines.
Sana Biotechnology, Inc. (NASDAQ:SANA) could possibly license its immune evasion technology to other companies or create its own medicines, generating several cash streams. Given the enormous potential ahead, the firm is undervalued, with a market valuation of $643 million as of February 25, a sound balance sheet, and support from some of the biggest biotech investors in the world. As the company continues to disclose survival data from its clinical trials and secure prospective licensing arrangements, it could potentially see tremendous upside.
Overall, SANA ranks 11th on our list of Jeff Bezos’ Investments in 2025. While we acknowledge the potential for SANA as an investment, our conviction lies in the belief that some AI stocks hold greater promise for delivering higher returns and doing so within a shorter time frame. If you are looking for an AI stock that is more promising than SANA but that trades at less than 5 times its earnings, check out our report about the cheapest AI stock.
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Disclosure: None. This article is originally published at Insider Monkey.