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Is Akebia Therapeutics (AKBA) One of the Best Penny Stocks to Buy

Akebia Therapeutics Inc. (NASDAQ:AKBA) is one of the 10 best penny stocks that could triple your money.

On February 26, Akebia Therapeutics Inc. (NASDAQ:AKBA) outlined its 2026 pipeline expansion and shared expectations for Vafseo data catalysts in the $1 billion dialysis market during its fourth quarter 2025 earnings call. The company reported a total of $227 million in net product revenue for the year, with Vafseo and Auryxia being major contributors.

hywards/Shutterstock.com

Chief Executive Officer John Butler reported that it was an important year for Akebia, particularly due to the commercialization of Vafseo. He also reported that there is increasing evidence of Vafseo’s potential for becoming standard of care in what is a $1 billion U.S. opportunity post-TDAPA, when Vafseo is expected to be priced at about parity with ESA pricing.

The company also announced its pipeline for rare kidney diseases, including an R&D day scheduled for April 2 to discuss mid-stage assets such as praliciguat and AKB-097. Butler stated:

“At the ASN meeting in November, we presented a post-hoc hierarchical composite endpoint analysis where patients treated with Vafseo experienced a lower risk of dying or being hospitalized than patients treated with the ESA comparator.”

On February 25, BTIG reduced the firm’s price target on Akebia Therapeutics Inc. (NASDAQ:AKBA) from $5 to $4. The firm maintained its Buy rating on the stock, citing a new protocol from U.S. Renal Care that impacted dosing practices, leading to a decline in channel inventory and lower-than-expected Q4 revenue for Vafseo. It added that the inventory adjustment weighed on near-term results despite the company’s broader outlook remaining intact.

Akebia Therapeutics Inc. (NASDAQ:AKBA) concentrates on the development and commercialization of medicines for kidney diseases. Its product portfolio includes Vafseo (vadadustat) and Auryxia. Additionally, it is working on AKB-10108 for the treatment of retinopathy of prematurity in neonates and AKB-9090 for treating cardiac surgery-related acute kidney injury and acute respiratory distress syndrome, which is undergoing Phase 2 of its clinical trial.

While we acknowledge the risk and potential of AKBA as an investment, our conviction lies in the belief that some AI stocks hold greater promise for delivering higher returns and doing so within a shorter time frame. If you are looking for an AI stock that is more promising than AKBA and that has 10,000% upside potential, check out our report about this cheapest AI stock.

READ NEXT: 33 Stocks That Should Double in 3 Years and 15 Stocks That Will Make You Rich in 10 Years.

Disclosure: None. Follow Insider Monkey on Google News.

The $250 Trillion AI Hype is Real. A few years from now, you’ll probably wish you’d bought this stock.

Dr. Inan Dogan

Dr. Ian Dogan

Co-Founder and Research Director at Insider Monkey

When Jeff Bezos said that one breakthrough technology would shape Amazon’s destiny, even Wall Street’s biggest analysts were caught off guard.

Fast forward a year and Amazon’s new CEO Andy Jassy described generative AI as a “once-in-a-lifetime” technology that is already being used across Amazon to reinvent customer experiences.

At the 8th Future Investment Initiative conference, Elon Musk predicted that by 2040 there would be at least 10 billion humanoid robots, with each priced between $20,000 and $25,000.

Do the math. According to Musk, this technology could be worth $250 trillion by 2040.

Put another way, that’s roughly equal to:

  • 175 Teslas
  • 107 Amazons
  • 140 Metas
  • 84 Googles
  • 65 Microsofts
  • And 55 Nvidias

And here’s the wild part — this $250 trillion wave isn’t tied to one company, but to an entire ecosystem of AI innovators set to reshape the global economy.

It’s a leap so massive, it could reshape how businesses, governments, and consumers operate worldwide.

Even if that $250 trillion figure sounds ambitious, major firms like PwC and McKinsey still see AI unlocking multi-trillion-dollar potential.

How could anything be worth that much?

The answer lies in a breakthrough so powerful it’s redefining how humanity works, learns, and creates.

And this breakthrough has already set off a frenzy among hedge funds and Wall Street’s top investors.

What most investors don’t realize is that one under-owned company holds the key to this $250 trillion revolution.

In fact, Verge argues this company’s supercheap AI technology should concern rivals.

Before I reveal the details, let’s talk about how some of the richest people on the planet are positioning themselves.

  • Bill Gates sees artificial intelligence as the “biggest technological advance in my lifetime,” more transformative than the internet or personal computer, capable of improving healthcare, education, and addressing climate change.
  • Larry Ellison — through Oracle, is spending billions on Nvidia chips and partnering with Cohere to embed generative AI across Oracle’s cloud and apps.
  • Warren Buffett — not known for tech hype — says this breakthrough could have a ‘hugely beneficial social impact.

When billionaires from Silicon Valley to Wall Street line up behind the same idea — you know it’s worth paying attention to.

Even as we admire what Tesla, Nvidia, Alphabet, and Microsoft have built, we believe an even greater opportunity lies elsewhere…

But the real story isn’t Nvidia — it’s a much smaller company quietly improving the critical technology that makes this entire revolution possible.

And judging by what I’m hearing from both Silicon Valley insiders and Wall Street veterans…

This prediction might not be bold at all:

A few years from now, you’ll wish you’d owned this stock.

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Dr. Inan Dogan

Dr. Ian Dogan

Co-Founder and Research Director at Insider Monkey

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Today, we have identified a nearly identical pattern in a digital-first giant trading at $3.

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