In this article, we will list the 5 Best US Stocks to Buy and Hold for the Next 3 Years. Please visit 8 Best US Stocks to Buy and Hold for the Next 3 Years to see the extended list and the methodology behind it.

5. CrowdStrike Holdings Inc. (NASDAQ:CRWD)

CrowdStrike Holdings Inc. (NASDAQ:CRWD) is one of the best US stocks to buy and hold for the next 3 years. On March 31, CrowdStrike and HCLTech expanded their partnership with the launch of Continuous Threat Exposure Management/CTEM services. This offering provides enterprises with an always-on view of their security posture by identifying, prioritizing, and remediating risks across endpoints, cloud, identity, applications, and data.

The services aim to help organizations address potential vulnerabilities in a structured and timely manner through intelligence-led insights. The collaboration integrates the AI-native CrowdStrike Falcon platform and its ExPRT.AI tech with HCLTech’s VERITY framework and AI Force platform. By combining advanced adversary intelligence with GenAI, the solution correlates threat and cloud posture signals to identify the attack paths most likely to be exploited.

This integration allows security teams to operationalize real-time insights and accelerate the remediation of critical exposures. Daniel Bernard of CrowdStrike Holdings Inc. (NASDAQ:CRWD) noted that the combination of the Falcon platform’s visibility and HCLTech’s service expertise allows customers to consolidate operations and move faster than adversaries. Amit Jain of HCLTech added that the integration of Agentic AI solutions ensures resilience for enterprises facing an evolving threat landscape.

CrowdStrike Holdings Inc. (NASDAQ:CRWD) is a technology company that offers cybersecurity solutions through its unified platform and a SaaS subscription-based model.

4. Vertiv Holdings Co. (NYSE:VRT)

Vertiv Holdings Co. (NYSE:VRT) is one of the best US stocks to buy and hold for the next 3 years. On March 30, Vertiv announced a ~$50 million investment to expand its manufacturing operations in Ironton, Ohio, and its global headquarters in Westerville, Ohio. This initiative supports the company’s critical digital infrastructure capabilities and is expected to create 100s of new jobs through 2029.

The expansion targets the growing demand for AI and high-density computing applications by strengthening Vertiv’s US production and supply chain. The Ironton facility expansion is scheduled to be operational by Q2 2027 and will increase production capacity for liquid cooling and chilled water systems by ~45%.

These advanced thermal management technologies are essential for supporting next-gen GPU clusters and large-scale model training. CEO Giordano Albertazzi emphasized that this investment enhances the company’s engineering, sales, and logistics capabilities. Vertiv Holdings Co. (NYSE:VRT) continues to focus on end-to-end solutions that manage power and cooling requirements from the grid to the individual chip.

Vertiv Holdings Co. (NYSE:VRT) is an electrical equipment & parts company that specializes in critical digital infrastructure technologies & life cycle services for data centers and communication networks

3. Arista Networks Inc. (NYSE:ANET)

Arista Networks Inc. (NYSE:ANET) is one of the best US stocks to buy and hold for the next 3 years. On March 12, Arista Networks announced the formation of a multi-source agreement/MSA for XPO, a revolutionary liquid-cooled pluggable optics module. Designed to meet the extreme bandwidth demands of AI networking, the XPO module delivers 12.8 Tbps of capacity and supports a front-panel density of 204.8 Tbps per rack unit.

This represents a 4x density improvement compared to existing 1600G-OSFP optics, providing a scalable solution for the rapid growth of AI data center fabrics. The XPO module introduces several key innovations, including an integrated cold plate capable of cooling up to 400W of power per module. It is a universal solution that supports all industry optics standards and next-gen architectures, offering flexibility for linear, half-retimed, or fully-retimed interfaces.

Chief Architect of Arista Networks Inc. (NYSE:ANET), Andreas Bechtolsheim, noted that XPO addresses the challenges of density and reliability as the industry transitions toward liquid-cooled environments. The XPO MSA is supported by major optical module suppliers, ensuring a robust ecosystem for the new form factor.

Arista Networks Inc. (NYSE:ANET) is a computer hardware company that develops client-to-cloud networking solutions for AI, data center, campus, and routing environments.

2. Amphenol Corporation (NYSE:APH)

Amphenol Corporation (NYSE:APH) is one of the best US stocks to buy and hold for the next 3 years. On March 24, Amphenol announced the pricing of a €500 million aggregate principal amount of senior notes due in 2031. These notes are being issued by its wholly owned German subsidiary, Amphenol Technologies Holding GmbH, and will be fully guaranteed by the parent company. The notes carry an annual interest rate of 3.625%.

The net proceeds from this offering are intended to be used for the repayment of Amphenol Corporation’s (NYSE:APH) outstanding 0.750% Euro Senior Notes that reach maturity in 2026. Additionally, the funds will be allocated toward general corporate purposes. The transaction is being managed by a group of joint book-running managers, including Barclays Bank PLC, Citigroup Global Markets Europe AG, Commerzbank Aktiengesellschaft, and HSBC Bank plc.

The notes are offered under an effective shelf registration statement previously filed with the Securities and Exchange Commission. Detailed terms of the offering will be provided in a prospectus supplement filed with the SEC. This announcement serves as a notice of pricing and does not constitute an official offer to sell or a solicitation to buy the securities in any jurisdiction where such an action would be unlawful.

Amphenol Corporation (NYSE:APH) is an electric components company that deals in electrical, electronic, and fiber optic connectors through the Communications Solutions, Harsh Environment Solutions, and Interconnect & Sensor Systems segments.

1. Eli Lilly and Company (NYSE:LLY)

Eli Lilly and Company (NYSE:LLY) is one of the best US stocks to buy and hold for the next 3 years. On March 31, Eli Lilly announced an agreement to acquire Centessa Pharmaceuticals in a deal valued at $7.8 billion. The acquisition diversifies the company’s portfolio beyond metabolic treatments and establishes a presence in the sleep disorder market. Eli Lilly has offered $38 per share in cash, representing a 37.8% premium over Centessa’s recent closing price, along with a contingent value right worth ~$9 per share.

The acquisition focuses on Centessa’s development of orexin agonists, a new class of treatments designed to regulate the brain’s sleep-wake cycle. The company’s lead drug candidate, cleminorexton, is currently in mid-stage clinical studies for the treatment of narcolepsy and idiopathic hypersomnia.

Analysts suggest that the market for narcolepsy drugs, currently valued at $2.5 billion, could expand with the introduction of these types of high-performance medical solutions. This deal follows several recent acquisitions by Eli Lilly and Company (NYSE:LLY) and aligns with the company’s efforts to address the widespread impact of sleep disorders, which affect an estimated 50 million to 70 million Americans.

Eli Lilly and Company (NYSE:LLY) is a healthcare company that specializes in human pharmaceutical products and offers cardiometabolic health & oncology products.

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