In this article, we will discuss the 10 Most Promising Stocks with Highest Upside Potential.

On June 16, Savita Subramanian, BofA Securities, joined CNBC’s ‘Power Lunch’ to discuss the overall market environment and whether earnings momentum can continue. While she clarified that she is not outright bearish and sees several attractive opportunities within the S&P 500, specifically recommending the Russell Large Cap Value index, she contended that it has become increasingly difficult to clock further gains from current levels. She outlined several reasons for this stance: good news is already priced in, tech sectors are beginning to experience multiple compressions, and supply-demand dynamics are shifting, with buybacks slowing down among hyperscalers.

Furthermore, Subramanian noted that the shrinkage of available public equity appears to be a trend of the past, and the liquidity spigot is being turned off as the market pivots from expecting Fed and central bank rate cuts to receiving none. She emphasized that while last year saw a record-breaking liquidity environment fueled by buying from individual investors, corporations, and the government, this year features less of that liquidity machine.

In response to a mention of Ed Yardeni’s recent FEMO (fabulous earnings momentum) thesis, Subramanian acknowledged that earnings have been strong, with a 30% increase in Q1, and that strong earnings can indeed fuel gains. However, she argued that the market reacts not just to earnings, but to surprises relative to expectations. She pointed out that analysts are currently forecasting close to the highest long-term earnings growth rates in the history of her data, making it difficult for companies to continue delivering the massive positive surprises that have previously driven the market. She notes that the market’s recent gains were driven by specific, major surprises, like the arrival of ChatGPT, the recovery from COVID, and government or Fed stimulus, and suggested that unless these levers are re-amplified, such as through a ChatGPT part 2, the potential for further upside surprises is limited.

Our Methodology

We used screeners to identify promising stocks that had an average upside potential of at least 45%. We limited our final selection to companies that have recently reported noteworthy developments likely to impact investor sentiment. These stocks are also popular among elite hedge funds and are ranked in ascending order of their upside potential.

Note: All data was sourced on June 19. 

Why are we interested in the stocks that hedge funds pile into? The reason is simple: our research has shown that we can outperform the market by imitating the top stock picks of the best hedge funds. Insider Monkey’s quarterly newsletter’s strategy selects 14 small-cap and large-cap stocks every quarter and has returned 599.2% since May 2014, beating its benchmark by 372 percentage points (see more details here).

10 Most Promising Stocks with Highest Upside Potential

10. Accenture (NYSE:ACN)

Average Upside Potential: 45.34%

Accenture (NYSE:ACN) is one of the most promising stocks with highest upside potential. On June 18, Accenture announced agreements to acquire a majority stake in Dragos, alongside full acquisitions of runZero and NetRise, for a combined enterprise value of ~$4.175 billion. This move aims to deliver a unified, end-to-end cybersecurity platform for “xOT” environments, which include the critical infrastructure and industrial systems that power energy grids, manufacturing, and data centers.

By integrating Dragos’s OT threat detection with runZero’s attack-surface intelligence and NetRise’s firmware and software supply chain visibility, Accenture aims to create a comprehensive solution for industrial operators. The combined platform will provide a single, vendor-neutral control plane that helps organizations visualize their networks, identify vulnerabilities, and proactively defend against AI-driven cyber threats and geopolitical risks.

These acquisitions significantly expand Accenture’s (NYSE:ACN) footprint from cybersecurity services into the broader OT software market, a sector projected to reach ~$59 billion by 2031. Dragos will continue to operate as an independent business under its current CEO, Robert M. Lee, while using Accenture’s global scale and deep industrial expertise to accelerate the protection of critical infrastructure worldwide.

Accenture (NYSE:ACN) is a global professional services company specializing in strategy, consulting, technology, and digital transformation. Headquartered in Dublin, Ireland, the company provides services in cloud computing, artificial intelligence, security, and operations, helping organizations modernize systems and drive innovation across industries.

9. Veeva Systems Inc. (NYSE:VEEV)

Average Upside Potential: 53.29%

Veeva Systems Inc. (NYSE:VEEV) is one of the most promising stocks with highest upside potential. On June 3, Veeva Systems reported strong financial results for its FQ1 2027, with total revenues reaching $882.9 million, a 16% increase year-over-year. Subscription revenues also saw steady growth, rising 15% to $730.2 million. The company exceeded its guidance across all metrics, leading to an increase in its full-year financial outlook.

The company is undergoing a strategic transformation from an industry-specific application provider to an AI agent company. Key progress includes the integration of conversational AI through the acquisition of Ostro, the upcoming expansion of Vault AI, and the planned early adopter release of Veeva Falcon in November, a platform designed to provide agentic labor for clinical, regulatory, and safety workflows.

Veeva Systems Inc.’s (NYSE:VEEV) commercial sector momentum remains strong, adding 27 new Vault CRM customers this quarter to surpass 150 live implementations. With raised guidance for the remainder of the fiscal year, management remains focused on using these agentic AI capabilities to help life sciences customers accelerate drug development and improve patient outcomes.

Veeva Systems Inc. (NYSE:VEEV) is a provider of cloud-based solutions for the global life sciences industry. Its offerings include cloud software, AI, data, and business consulting.

8. Royal Gold Inc. (NASDAQ:RGLD)

Average Upside Potential: 53.85%

Royal Gold Inc. (NASDAQ:RGLD) is one of the most promising stocks with highest upside potential. On May 18, Royal Gold restructured its ownership in the Hod Maden gold-copper project in Türkiye, reducing its direct equity in the joint venture company, Artmin, from 30% to 15%. Under the new agreement, SSR Mining will sell its interest to partner Lidya Madençilik, which will assume full operatorship. In exchange, Royal Gold secures a new 2.5% net smelter return/NSR royalty, while SSR receives a 4.0% NSR royalty.

This restructuring is designed to preserve the value of Royal Gold’s stake while reducing its exposure to capital and operating costs. As part of the deal, Royal Gold gains specific rights regarding the SSR royalty, including a right of first refusal on its sale and an option to acquire half of it for $160 million. The company expects the project to remain a meaningful contributor to its portfolio, projecting approximately 9,000 gold equivalent ounces annually during the first 5 years of production.

The transaction, expected to close in H2 2026, aligns the project with Lidya, an experienced local operator with the resources to advance the high-grade development. While Royal Gold Inc. (NASDAQ:RGLD) will fund the next $70 million of project costs, the overall burden remains manageable given the project’s high-margin potential and 13-year mine life, despite the increase in the total private royalty burden on the asset.

Royal Gold Inc. (NASDAQ:RGLD) is involved in the acquisition and management of precious metal streams, royalties, and similar interests. Its operations are divided into the Acquisition and Management of Stream Interests and the Acquisition and Management of Royalty Interests segments.

7. BioMarin Pharmaceutical Inc. (NASDAQ:BMRN)

Average Upside Potential: 55.42%

BioMarin Pharmaceutical Inc. (NASDAQ:BMRN) is one of the most promising stocks with highest upside potential. On June 16, BioMarin presented new clinical data at ENDO 2026, highlighting progress in its treatments for skeletal dysplasias. An investigator-led Phase 2 extension study showed that three years of treatment with VOXZOGO (vosoritide) resulted in sustained improvements in annualized growth velocity and height standard deviation scores for children with hypochondroplasia.

These findings build on recent positive Phase 3 results, with the company planning to submit a supplemental NDA to the FDA in Q3 2026. The company also shared Phase 1 data for BMN 333, an investigational long-acting C-type natriuretic peptide/CNP for achondroplasia. Results from a single-ascending dose study showed that BMN 333 provided sustained systemic exposure, supporting a potential weekly dosing schedule.

The treatment was well tolerated, and its ability to significantly increase free CNP exposure compared to existing therapies suggests it could become a new standard of care. Enrollment is currently underway for a registration-enabling Phase 2/3 study. These developments reinforce BioMarin Pharmaceutical Inc.’s (NASDAQ:BMRN) commitment to addressing growth-related skeletal conditions where few or no approved medical treatments currently exist.

BioMarin Pharmaceutical Inc. (NASDAQ:BMRN) develops and commercializes therapies for serious and life-threatening medical conditions and rare diseases. The company’s product pipeline includes Valoctocogene roxaparvovec, Vosoritide, and BMN 307.

6. PTC Inc. (NASDAQ:PTC)

Average Upside Potential: 56.86%

PTC Inc. (NASDAQ:PTC) is one of the most promising stocks with highest upside potential. On June 11, PTC launched PTC Orbit, a cloud-native “as-maintained” system of intelligence designed to bridge the gap between product design and real-world asset performance. By unifying data from siloed enterprise systems (including PLM, ERP, CRM, IoT, EAM, and FSM), the platform creates a single, accurate record for each asset, allowing manufacturers to maintain visibility long after a product has shipped.

The solution is built with an “AI-first” approach to transform fragmented data into actionable insights. PTC Orbit uses AI to detect service patterns, identify failure trends, and calculate asset health scores, while its AI-powered interface allows teams across engineering, quality, and service departments to dynamically query asset data and investigate issues. This replaces static dashboards with a responsive, context-aware environment that supports proactive maintenance and reliability programs.

By enabling this level of closed-loop intelligence, PTC Orbit aims to help manufacturers move from reactive operations to insight-led decision-making. The platform is a central component of PTC Inc.’s (NASDAQ:PTC) “Intelligent Product Lifecycle” vision, providing the data foundation necessary for companies to optimize field service activity, reduce asset risk, and drive aftermarket revenue through more informed, data-driven strategies.

PTC Inc. (NASDAQ:PTC) is a global software company headquartered in Boston, Massachusetts, and was founded in 1985. The company specializes in product lifecycle management/PLM, computer-aided design, and industrial IoT solutions.

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