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10 Cities with the Lowest Life Expectancy in the US

In this article, we look at 10 cities with the lowest life expectancy in the US. You can read about the research and development going on in the pharmaceutical industry to enhance longevity by heading over to the 40 Cities with the Lowest Life Expectancy in the US.

10. Chattanooga, TN-GA

Principal City: Chattanooga

Life Expectancy: 76

The Chattanooga metropolitan area comprises six counties – three of them in southwest Tennessee while three in northwest Georgia. Residents at birth are expected to live for 76 years, which is well below the national average in the United States of 77.5 years.

9. Spartanburg, SC

Principal City: Spartanburg

Life Expectancy: 75.9

There is immense disparity in life expectancy in Spartanburg, where people living in affluent neighborhoods live up to 85 years, whereas in some poorer localities, the average lifespan plummets to as low as 67 years. Spartanburg is among cities with the lowest life expectancy in the US.

8. Little Rock-North Little Rock-Conway, AR

Principal City: Little Rock

Life Expectancy: 75.6

The Little Rock Metro, which is also known as Central Arkansas, has one of the lowest life expectancies in the United States, where residents at birth are forecasted to live two years less than an average American.

7. Memphis, TN-MS-AR

Principal City: Memphis

Life Expectancy: 75.5

According to United Healthcare, Tennessee ranks 44th in the US for overall health facilities, with a high number of premature deaths. Moreover, between 2019 and 2020, there was a 44% increase in deaths due to drug overdose. Given the circumstances and medical facilities at disposal, it is no surprise that Memphis finds itself in the list of cities with the lowest life expectancy in the US.

6. Knoxville, TN

Principal City: Knoxville

Life Expectancy: 75.5

Next on our list is another city from Tennessee, Knoxville, where residents have a life expectancy of 75.5 years, which is slightly above the state average of 75, but well below the lifespan of an average US citizen.

5. Beaumont-Port Arthur, TX

Principal City: Beaumont

Life Expectancy: 75.2

The Beaumont-Port Arthur metro area in Texas has a population of approximately 393,000 people. People born in this part of the country are expected to have a lifespan that is two years and three months shorter than the national average of the US.

4. Montgomery, AL

Principal City: Montgomery

Life Expectancy: 74.7

According to US News, 11.7% of the population in Montgomery, Alabama do not have health insurance. The smoking rate is estimated to be over 20%, while 451 in every 100,000 residents suffer from cancer. Prevalence of heart diseases is 6.2%, which is higher than the national average in the US of 6.1%.

3. Birmingham-Hoover, AL

Principal City: Birmingham

Life Expectancy: 74.6

The Birmingham metropolitan area in Alabama has one of the shortest life expectancies in the United States, with residents at birth expected to live for only 74.6 years, which is nearly three years less than the average lifespan in the United States.

2. Mobile, AL

Principal City: Mobile

Life Expectancy: 74.4

The port city of Mobile in Alabama has a population of nearly 430,000 people, where residents have an average lifespan of 74.4 years – joint lowest with Jackson in Mississippi among the large metropolitans of the United States. The state of Alabama has one of the lowest life expectancies in the US of just 73.2 years.

1. Jackson, MS

Principal City: Jackson

Life Expectancy: 74.4

Mississippi’s capital city Jackson has the worst life expectancy among large metropolitan cities in the United States, where people at birth are expected to live three years less than an average American citizen. Jackson is also one of the poorest cities in the US.

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The $250 Trillion AI Hype is Real. A few years from now, you’ll probably wish you’d bought this stock.

Dr. Inan Dogan

Dr. Ian Dogan

Co-Founder and Research Director at Insider Monkey

When Jeff Bezos said that one breakthrough technology would shape Amazon’s destiny, even Wall Street’s biggest analysts were caught off guard.

Fast forward a year and Amazon’s new CEO Andy Jassy described generative AI as a “once-in-a-lifetime” technology that is already being used across Amazon to reinvent customer experiences.

At the 8th Future Investment Initiative conference, Elon Musk predicted that by 2040 there would be at least 10 billion humanoid robots, with each priced between $20,000 and $25,000.

Do the math. According to Musk, this technology could be worth $250 trillion by 2040.

Put another way, that’s roughly equal to:

  • 175 Teslas
  • 107 Amazons
  • 140 Metas
  • 84 Googles
  • 65 Microsofts
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And here’s the wild part — this $250 trillion wave isn’t tied to one company, but to an entire ecosystem of AI innovators set to reshape the global economy.

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Even if that $250 trillion figure sounds ambitious, major firms like PwC and McKinsey still see AI unlocking multi-trillion-dollar potential.

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  • Bill Gates sees artificial intelligence as the “biggest technological advance in my lifetime,” more transformative than the internet or personal computer, capable of improving healthcare, education, and addressing climate change.
  • Larry Ellison — through Oracle, is spending billions on Nvidia chips and partnering with Cohere to embed generative AI across Oracle’s cloud and apps.
  • Warren Buffett — not known for tech hype — says this breakthrough could have a ‘hugely beneficial social impact.

When billionaires from Silicon Valley to Wall Street line up behind the same idea — you know it’s worth paying attention to.

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Dr. Inan Dogan

Dr. Ian Dogan

Co-Founder and Research Director at Insider Monkey

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