Isis Pharmaceuticals Inc

Insider Trading: Sales

Symbol	Price	Amount	Total Value	Remaining Holdings	Date	Form 4
RGLS	$6.95	1,650	$11,470.64	6,975,000	2014-09-03	Filing
"RGLS"	$6.84	1,500	$10,254.00	6,976,650	2014-08-29	Filing
"RGLS"	$6.96	2,000	$13,920.80	6,978,150	2014-08-28	Filing
"RGLS"	$7.21	1,500	$10,821.45	6,980,150	2014-08-27	Filing
"RGLS"	$6.75	5,250	$35,442.75	6,981,650	2014-08-22	Filing
"RGLS"	$6.89	2,500	$17,222.25	6,986,900	2014-08-21	Filing
"RGLS"	$7.14	3,000	$21,423.60	6,989,400	2014-08-20	Filing
"RGLS"	$6.98	1,450	$10,115.35	6,992,400	2014-08-15	Filing
"RGLS"	$7.04	1,750	$12,324.03	6,993,850	2014-08-14	Filing
"RGLS"	$7.02	2,250	$15,787.58	6,995,600	2014-08-13	Filing
"RGLS"	$6.80	1,850	$12,582.59	6,997,850	2014-08-08	Filing
"RGLS"	$6.66	2,600	$17,321.98	6,999,700	2014-08-07	Filing
"RGLS"	$7.08	3,150	$22,300.11	7,002,300	2014-08-06	Filing
"RGLS"	$6.21	2,600	$16,152.50	7,005,450	2014-08-01	Filing
"RGLS"	$6.42	1,750	$11,234.65	7,008,050	2014-07-31	Filing
"RGLS"	$6.60	1,000	$6,602.10	7,009,800	2014-07-30	Filing
"RGLS"	$6.55	1,700	$11,136.53	7,010,800	2014-07-25	Filing
"RGLS"	$6.81	1,850	$12,597.95	7,012,500	2014-07-24	Filing
"RGLS"	$6.88	1,700	$11,701.95	7,014,350	2014-07-23	Filing
"RGLS"	$6.80	5,000	$34,001.00	7,016,050	2014-07-18	Filing