| Company | Symbol | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
| VRTX | $193.24 | 1,076 | Officer | 12,430 | 2018-10-01 | Filing |
| VRTX | $149.95 | 777 | Officer | 8,789 | 2018-01-02 | Filing |
| IRWD | $16.94 | 1,417 | Officer | 20,763 | 2017-02-22 | Filing |
| IRWD | $16.94 | 457 | Officer | 22,180 | 2017-02-22 | Filing |