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Filing Details

Issuer

Cik	Name	Symbol	Sector (SIC)	IRS No
1649904	Rhythm Pharmaceuticals Inc.	RYTM	Pharmaceutical Preparations (2834)	462159271

Insiders

Cik	Name	Reported Address	Insider Title	Director	Officer	Large Shareholder	Other
2027261	Alastair Garfield	222 Berkeley Street, 12Th Floor Boston MA 02116	Chief Scientific Officer	No	Yes	No	No

Transaction Summary

Sold:	1,319 shares	Avg. Price: $64.81	Total Value: $85,483.13
Number of Shares After Transactions:	3,126 shares

Reported Non-Derivative Transactions

Sec. Name	Acquisiton - Disposition	Date	Amount	Price	Remaning Holdings	Equity Swap Involved	Form Type	Code	Nature of Ownership
Common Stock	Acquisiton	2025-07-01	4,445	$0.00	4,445	No	4	M	Direct
Common Stock	Disposition	2025-07-02	1,313	$64.81	3,132	No	4	S	Direct
Common Stock	Disposition	2025-07-02	6	$64.60	3,126	No	4	S	Direct

Equity Swap Involved	Form Type	Code	Nature of Ownership
No	4	M	Direct
No	4	S	Direct
No	4	S	Direct

Reported Derivative Transactions

Sec. Name	Sec. Type	Acquisiton - Disposition	Date	Amount	Price	Amount - 2	Price - 2
Common Stock	Restricted Stock Units	Disposition	2025-07-01	4,445	$0.00	4,445	$0.00

Remaning Holdings	Exercise Date	Expiration Date	Equity Swap Involved	Transaction Form Type	Transaction Code	Nature of Ownership
13,333			No	4	M	Direct

Footnotes

Each restricted stock unit represents a contingent right to receive one share of Issuer common stock.
The sale reported in this Form 4 was effected pursuant to Rule 10b5-1 instruction adopted on June 25, 2024 solely with the intent to cover withholding taxes in connection with the vesting of certain previously reported restricted stock units.
The restricted stock units vest as to 25% of the total restricted stock units on each of the first four anniversaries of July 1, 2024, subject to the Reporting Person's continued service on each such vesting date. The restricted stock units have no expiration date.