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Filing Details

Issuer

Cik	Name	Symbol	Sector (SIC)	IRS No
875320	Vertex Pharmaceuticals Inc / Ma	VRTX	Pharmaceutical Preparations (2834)	043039129

Insiders

Cik	Name	Reported Address	Insider Title	Director	Officer	Large Shareholder	Other
1550395	David Altshuler	C/O Vertex Pharmaceuticals Incorporated 50 Northern Avenue Boston MA 02210	Evp, Global Research And Cso	No	Yes	No	No

Reported Non-Derivative Transactions

Sec. Name	Acquisiton - Disposition	Date	Amount	Price	Remaning Holdings	Equity Swap Involved	Form Type	Code	Nature of Ownership
Common Stock	Disposition	2023-02-17	3,750	$292.85	44,248	No	4	F	Direct
Common Stock	Disposition	2023-02-21	36	$291.01	44,212	No	4	S	Direct
Common Stock	Disposition	2023-02-21	1,223	$292.76	42,989	No	4	S	Direct
Common Stock	Disposition	2023-02-21	1,843	$294.03	41,146	No	4	S	Direct
Common Stock	Disposition	2023-02-21	900	$294.73	40,246	No	4	S	Direct

Equity Swap Involved	Form Type	Code	Nature of Ownership
No	4	F	Direct
No	4	S	Direct
No	4	S	Direct
No	4	S	Direct
No	4	S	Direct

Footnotes

Transaction made pursuant to Dr. Altshuler's company approved trading plan under Rule 10b5-1.
Dr. Altshuler undertakes to provide (upon request by the SEC staff, the issuer or a security holder of the issuer) full information regarding the number of shares sold at each separate price.
Open market sales reported on this line occurred at a weighted average price of $292.76 (range $292.25 to $293.12).
Open market sales reported on this line occurred at a weighted average price of $294.03 (range $293.45 to $294.42).
Open market sales reported on this line occurred at a weighted average price of $294.73 (range $294.47 to $295.37).