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Filing Details

Issuer

Cik	Name	Symbol	Sector (SIC)	IRS No
1785530	Werewolf Therapeutics Inc.	HOWL	()	L3

Insiders

Cik	Name	Reported Address	Director	Officer	Large Shareholder	Other
1496201	Ltd. Management Funds Sphera	C/O Sphera Funds Management Ltd. 21 Ha'Arba'Ah Street Tel Aviv L3 64739	No	No	Yes	No
1599854	Sphera Global Healthcare Management Lp	C/O Sphera Funds Management Ltd. 21 Ha'Arba'Ah Street Tel Aviv L3 64739	No	No	Yes	No
1599855	Ltd. Gp Healthcare Global Sphera	C/O Sphera Funds Management Ltd. 21 Ha'Arba'Ah Street Tel Aviv L3 64739	No	No	Yes	No

Reported Non-Derivative Transactions

Sec. Name	Acquisiton - Disposition	Date	Amount	Price	Remaning Holdings	Equity Swap Involved	Form Type	Code	Nature of Ownership	Explanation
Common Stock	Acquisiton	2021-05-04	312,997	$0.00	312,997	No	4	C	Indirect	See footnote
Common Stock	Acquisiton	2021-05-04	475,000	$16.00	787,997	No	4	P	Indirect	See footnote

Equity Swap Involved	Form Type	Code	Nature of Ownership	Explanation
No	4	C	Indirect	See footnote
No	4	P	Indirect	See footnote

Reported Derivative Transactions

Sec. Name	Sec. Type	Acquisiton - Disposition	Date	Amount	Price	Amount - 2	Price - 2
Common Stock	Series B Preferred Stock	Disposition	2021-05-04	2,713,410	$0.00	312,997	$0.00

Remaning Holdings	Exercise Date	Expiration Date	Equity Swap Involved	Transaction Form Type	Transaction Code	Nature of Ownership
0			No	4	C	Indirect

Footnotes

Includes (a) 187,798 shares held by Sphera Global Healthcare Master Fund (the "Healthcare Fund") and (b) 125,199 shares held by SpheraBiotech Master Fund, LP (the "Biotech Fund" and, together with the Healthcare Fund, the "Funds").
On May 4, 2021, the Series B Preferred Stock automatically converted into Common Stock on a 8.6691-for-one basis without payment of further consideration upon closing of the initial public offering of the Issuer's common stock. The shares had no expiration date.
Sphera Global Healthcare Management LP is the investment manager for the Funds (the "Management Company"). The Management Company is managed, controlled and operated by its general partner Sphera Global Healthcare GP Ltd. (the "General Partner"), of which Sphera Funds Management Ltd. ("SFML") is the controlling shareholder. Each of the Management Company, the General Partner and SFML may be deemed the indirect beneficial owner of the reported securities for purposes of Section 13(d) of the Securities Exchange Act of 1934, as amended.
Includes (a) 300,000 shares held by the Healthcare Fund and (b) 175,000 shares held by the Biotech Fund.
Includes (a) 487,798 shares held by the Healthcare Fund and (b) 300,199 shares held by Biotech Fund.